Results 31 to 40 of about 19,535,634 (199)

The roles and applications of extracellular vesicles in cancer

Molecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

450-nm GaN laser diode enables high-speed visible light communication with 9-Gbps QAM-OFDM.

Optics Express, 2015
A TO-38-can packaged Gallium nitride (GaN) blue laser diode (LD) based free-space visible light communication (VLC) with 64-quadrature amplitude modulation (QAM) and 32-subcarrier orthogonal frequency division multiplexing (OFDM) transmission at 9 Gbps ...
Yu-Chieh Chi, D. Hsieh, Cheng-Ting Tsai, Hsiang-Yu Chen, H. Kuo, Gong-Ru Lin   +5 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Seipin is required for converting nascent to mature lipid droplets

eLife, 2016
How proteins control the biogenesis of cellular lipid droplets (LDs) is poorly understood. Using Drosophila and human cells, we show here that seipin, an ER protein implicated in LD biology, mediates a discrete step in LD formation—the conversion of ...
Huajin Wang, Michel Becuwe, B. Housden, Chandramohan Chitraju, Ashley J. Porras, Morven M. Graham, Xinran Liu, A. Thiam, D. Savage, A. Agarwal, A. Garg, Maria-Jesus Olarte, Qingqing Lin, F. Fröhlich, H. Hannibal-Bach, S. Upadhyayula, N. Perrimon, T. Kirchhausen, Christer S. Ejsing, T. Walther, Robert V Farese   +20 more
semanticscholar   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

Characterization of the Ld-restricted cytotoxic T-lymphocyte epitope in the mouse hepatitis virus nucleocapsid protein

Journal of Virology, 1993
The mouse hepatitis virus (MHV) JHM strain (JHMV) produces primary demyelination in the central nervous system associated with acute encephalomyelitis. Humoral and cellular immune responses both participate in controlling the development of chronic MHV ...
C. Bergmann, M. Mcmillan, S. Stohlman
semanticscholar   +1 more source

Expert panel on monitoring radiation doses from recurrent medical diagnostic procedures: Sixth Gilbert W. Beebe Webinar

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Recurrent imaging is an essential tool for patient care but with an attendant dose from radiation exposure. Recurrent imaging has been the subject of increasing scrutiny and debate based largely on the risk from increasing cumulative doses. However, the accountability for and actions with recurrent imaging as a special component in the general
Donald P. Frush, Armin Ansari, James A. Brink, Ourania Kosti, David B. Larson, Martha S. Linet, Mahadevappa Mahesh, Ioannis Sechopoulos, Jenia Vassileva   +8 more
wiley   +1 more source

Evolutionary History of GS3, a Gene Conferring Grain Length in Rice

Genetics, 2009
Unlike maize and wheat, where artificial selection is associated with an almost uniform increase in seed or grain size, domesticated rice exhibits dramatic phenotypic diversity for grain size and shape.
Noriko Takano-Kai, Hui Jiang, T. Kubo, Megan T Sweeney, T. Matsumoto, H. Kanamori, Badri K. Padhukasahasram, C. Bustamante, A. Yoshimura, K. Doi, S. McCouch   +10 more
semanticscholar   +1 more source

Characterization, commissioning, and clinical evaluation of a commercial BeO optically stimulated luminescence (OSL) system

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract This article investigates the performance of a commercial BeO optically stimulated luminescent (OSL) dosimetry system (myOSLchip, RadPro GmbH International, Remscheid, Germany) through the application of the commissioning framework for luminescent dosimeters as described in the American Association of Physicists in Medicine Task Group 191 ...
Joseph P. Kowalski, Brett G. Erickson, Qiuwen Wu, Xinyi Li, Sua Yoo   +4 more
wiley   +1 more source

Secondary cell-mediated lympholysis: importance of H-2 LD and SD factors

Journal of Experimental Medicine, 1976
Lymphocytes stimulated in mixed leukocyte cultures and left for 13-17 days, i.e. beyond their peak proliferative and cytotoxic reactivities, can be restimulated to give a secondary-type rapid and strong proliferative and cytotoxic response when ...
B. Alter, C. Grillot‐Courvalin, M. Bach, K. Zier, P. Sondel, F. Bach   +5 more
semanticscholar   +1 more source