Does Pentraxin-3 contribute to the reduction of low-density lipoprotein levels by statin therapy? [PDF]
Statins have been shown to decrease inflammatory markers, especially high sensitivity C reactive protein (hsCRP), in a dose-dependent manner. Pentraxin-3 (PTX3) is another important inflammatory biomarker from the pentraxin family that provides useful ...
Vuković-Dejanović Vesna +3 more
doaj +1 more source
LDL-C target attainment in the total cohort and stratified by risk as observed and simulated.
LDL-C concentrations are given as median (interquartile range). LDL-C: Low-density lipoprotein cholesterol. LLT: Lipid-lowering therapy.
Aikaterini Bilitou (5785471) +3 more
core +1 more source
LDL-C Targets in Secondary Prevention: How Low Should We Go?
The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well ...
Mohamed B. Elshazly (14151951) +8 more
core +1 more source
Nicotine regulates PCSK9 expression in HepG2 cells through Raf/MEK/ERK signaling pathway
Objective To investigate the effect of nicotine (NIC) on the expression of proprotein convertase subtilisin/kexin type 9 (PCSK9) and its molecular mechanism.
ZHOU Lin +4 more
doaj +1 more source
Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes [PDF]
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease.
B. O’Malley +22 more
core +1 more source
Alternate Day versus Once Daily Atorvastatin for Primary Prevention of (CHD) in Naïve Patients of Dyslipidemia [PDF]
Introduction: Statins (or HMG-CoA reductase inhibitors) have become drug of choice for raised Low-Density Lipoprotein Cholesterol (LDL-C) in treating.
Canna Jagdish Ghia +4 more
doaj +1 more source
Comparison between Values of Low Density Lipoprotein Cholesterol as Estimated by Direct Enzymatic Method with Calculated Methods Applying Friedewald’s Equation and Novel’s Equation: A Cross-sectional Study [PDF]
Introduction: Lipid profile is routinely used as a screening test to identify the risk of Cardiovascular Diseases (CVD). Elevated Low Density Lipoprotein cholesterol (LDL-c) is an important modifiable risk factor of atherosclerotic CVD.
Maithri Chikkabasavanahalli Manjegowda +3 more
doaj +1 more source
LDL-C response by 6-month treatment of statin or statin + ezetimibe.
LDL-C response by 6-month treatment of statin or statin + ezetimibe.
Joo-Hee Zo (721373) +5 more
core +1 more source
OBJETIVO: Avaliar a dosagem direta do colesterol LDL (LDL-C) por um método homogêneo, em comparação com a estimativa pela fórmula de Friedewald, em uma grande população heterogênea.
Caio Maurício Mendes de Cordova +3 more
doaj +1 more source
Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
core +1 more source

