Results 11 to 20 of about 248,151 (219)

Cholesterol delivered to macrophages by oxidized low density lipoprotein is sequestered in lysosomes and fails to efflux normally

open access: yesJournal of Lipid Research, 2000
Oxidized low density lipoprotein (LDL) has been found to exhibit numerous potentially atherogenic properties, including transformation of macrophages to foam cells.
Baljinder S. Dhaliwal   +1 more
doaj   +1 more source

Association between low-density lipoprotein cholesterol and sudden cardiac arrest in people with diabetes mellitus

open access: yesCardiovascular Diabetology, 2023
Background Dyslipidemia measured as low-density lipoprotein (LDL)-cholesterol is an established risk factor of cardiovascular disease, which is more pronounced in diabetes population.
Yun Gi Kim   +9 more
doaj   +1 more source

LDL particle size and LDL and HDL cholesterol changes with dietary fat and cholesterol in healthy subjects

open access: yesJournal of Lipid Research, 1998
We have conducted a dietary trial in 54 men and 51 women with a wide range of fasting cholesterol values to examine the use of low density lipoprotein (LDL) particle size to predict the lipoprotein response to dietary fat and cholesterol.
Peter M. Clifton   +2 more
doaj   +1 more source

Decrease of LDL Cholesterol Through The Increase of HDL Cholesterol by Administering Garcinia mangostana L. Peel Extract in White Mice

open access: yesFolia Medica Indonesiana, 2021
Highlight: • Ethanol extract of Garcinia mangostana L. peel reduce malondialdehyde. • Garcinia mangostana L. peel extract can increase non-radical products which impact in decreasing LDL cholesterol and increasing HDL cholesterol.
Hasyim As'ari
doaj   +1 more source

Cholesterol deposition in macrophages: foam cell formation mediated by cholesterol-enriched oxidized low density lipoprotein.

open access: yesJournal of Lipid Research, 1997
Oxidized low density lipoprotein (LDL) is thought to mediate the transformation of macrophages to cholesterol-rich foam cells. Yet convincing evidence for this process is lacking in vitro.
P Greenspan, H Yu, F Mao, R L Gutman
doaj   +1 more source

Lipoprotein metabolism in familial hypercholesterolemia: Serial assessment using a one-step ultracentrifugation method

open access: yesPractical Laboratory Medicine, 2015
Objectives: It is well known that familial hypercholesterolemia (FH) is a common inherited disorder that can markedly elevate the level of plasma LDL cholesterol.
Hayato Tada   +6 more
doaj   +1 more source

Influence of an atherogenic diet on the structure of swine low density lipoproteins

open access: yesJournal of Lipid Research, 1980
Five groups of three swine each were fed a basal diet supplemented with 15% tallow and either 0.0, 1.0, 1.5, 2.0%, or 2.5% cholesterol. The animals were studied over a period of 9 weeks to observe changes in plasma lipids and low density lipoproteins ...
H J Pownall   +5 more
doaj   +1 more source

Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels

open access: yesJournal of Lipid Research, 2010
Over the past several years, proprotein convertase subtilisin kexin type 9 (PCSK9) has gained significant attention as a key regulator of serum LDL-cholesterol (LDL-C) levels.
Jason S. Troutt   +3 more
doaj   +1 more source

Interaction of aging and dietary fat in the regulation of low density lipoprotein transport in the hamster.

open access: yesJournal of Lipid Research, 1989
These studies were undertaken to examine the effect of aging on low density lipoprotein (LDL) metabolism in the male hamster. When the hamsters were maintained on a low-cholesterol, low-triglyceride diet, rates of LDL transport in the various tissues of ...
D K Spady, J M Dietschy
doaj   +1 more source

Cellular cholesterol efflux and cholesterol loading capacity of serum: effects of LDL-apheresis

open access: yesJournal of Lipid Research, 2012
High LDL-cholesterol (LDL-C) characterizes familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH). LDL-apheresis, used in these patients to reduce LDL-C levels, has been shown to also affect HDL levels and composition.
M.P. Adorni   +9 more
doaj   +1 more source

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