Results 201 to 210 of about 370,495 (313)

Lipid lowering in coronary artery disease - not just statins. [PDF]

open access: yesClin Med (Lond)
Han J, Masmanian E, Wang T, Chua TP.
europepmc   +1 more source

Associations of C‐Reactive Protein–Triglyceride–Glucose Index With the Incidence and Progression of Cardiometabolic Multimorbidity in Middle‐Aged and Older Chinese Individuals: A Prospective Cohort Study From CHARLS

open access: yesiLABMED, EarlyView.
This study investigated the association between C‐reactive protein‐triglyceride‐glucose index (CTI) and cardiometabolic multimorbidity (CMM) over a 9‐year follow‐up in a Chinese middle‐aged and older population. Higher CTI levels were significantly associated with an increased risk of CMM.
Zhengfeng Wu   +6 more
wiley   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

open access: yesiMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian   +7 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

TRIM31–LOX‐1 Axis: A Novel Therapeutic Frontier in Atherosclerosis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Atherosclerosis, driven by a vicious cycle of lipid accumulation and chronic inflammation, underlies most cardiovascular diseases. Macrophages exacerbate this process by internalizing oxidized low‐density lipoprotein (oxLDL), forming foam cells, and releasing inflammatory mediators. A recent study published in Circulation identified the TRIM31–
Qian Zhang, Cheng Xue Qin
wiley   +1 more source

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