Results 91 to 100 of about 111,529 (192)

The effect of selective low-density lipoprotein apheresis on plasma lipoperoxides and antioxidant vitamins in familial hypercholesterolemic patients

, 1998
Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder characterized by a lifelong elevation in the concentration of low-density lipoprotein (LDL) bound cholesterol in blood by cholesterol deposits and by early coronary artery ...
RIVASI P., PIZZALA, ROBERTO, TOMASI A., CACCIAVILLANI G., BARICCHI R.   +4 more
core  

Population Pharmacokinetics and Exposure‐Response Modeling for Evinacumab in Children, Adolescents, and Adults With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics & Systems Pharmacology
Evinacumab, an angiopoietin‐like 3 (ANGPTL3) inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C), independent of low‐density lipoprotein receptor, in patients with homozygous familial hypercholesterolemia (HoFH).
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Yuhuan Wang, Poulabi Banerjee, Robert Pordy, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +8 more
doaj   +1 more source

Low-Density Lipoprotein Apheresis in Patients with Acute Kidney Injury Due to Minimal Change Disease Requiring Acute Renal Replacement Therapy

International Journal of Nephrology and Renovascular Disease, 2020
Kohsuke Terada, Koji Mugishima, Sayuri Kawasaki, Fumiaki Itagaki, Takehisa Yamada, Yukinao Sakai Department of Nephrology, Graduate School of Medicine, Nippon Medical School, Tokyo, JapanCorrespondence: Yukinao SakaiDepartment of Nephrology, Graduate ...
Terada K, Mugishima K, Kawasaki S, Itagaki F, Yamada T, Sakai Y   +5 more
doaj  

Outpatient monthly plasmapheresis with post-PLEX evinacumab in pediatric homozygous familial hypercholesterolemia: a case report on port access and immunoglobulin preservation

Frontiers in Pediatrics
Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by severely elevated low-density lipoprotein (LDL) cholesterol levels, predisposing patients to early cardiovascular disease.
Guido Filler, Kambiz Norozi, Kambiz Norozi   +2 more
doaj   +1 more source

Treatment of symptomatic HyperLp(a)lipoproteinemia with LDL-apheresis: a multicentre study

, 2009
LDL-apheresis (LDLa) efficacy in the treatment of symptomatic HyperLp(a)lipoproteinemia -HyperLp(a)- has been studied in a multicentre trial. After 3.1 +/- 2.7 years of weekly and biweekly treatment, the data from 19 patients (males: 12; females: 7; aged
G. Dalessandri, STEFANUTTI, Claudia, M. G. Zenti, D. Belotherkovsky, A. Vivenzio, S. Di Giacomo, G. De Silvestro, P. Marson, G. Russi   +8 more
core   +1 more source

CLINICAL APPLICATION OF HELP-APHERESIS IN FEMALE PATIENT WITH FAMILIAL HYPERCHOLESTEROLEMIA

Фундаментальная и клиническая медицина, 2018
Cardiovascular diseases caused by atherosclerosis and its complications represent the leading cause of death in developed countries. The main risk factor of atherosclerosis development is dyslipidemia, in particular familial hypercholesterolemia (FH ...
OLGA L. Barbarash, NATALIA V. Fedorova, VASILIY V. Kashtalap, ROMAN A. Kornelyuk, OLESYA E. Astafurova, DMITRIY L. Shukevich, OLGA V. Gruzdeva   +6 more
doaj  

Abstracts of the 18th SCWD Conference, 11‐13 December 2025 in Rome/Italy

JCSM Communications, Volume 9, Issue 1, January/June 2026.
wiley   +1 more source

LDL-apheresis: Comparison of methods

, 1998
Elective treatment for patients affected with familial hyper- cholesterolemia, in addition to drug therapy, is the removal of cholesterol by apheresis. This can be obtained by selective, semiselective or non- selective techniques.
Sartore G., Ongaro G., Marson P., De Silvestro G., Gabelli C.   +4 more
core  

Long-term effectiveness and safety of lomitapide in patients with homozygous familial hypercholesterolemia: an observational case series

Orphanet Journal of Rare Diseases
Background We assessed long-term real-world effectiveness and safety of lomitapide in patients with homozygous familial hypercholesterolemia (HoFH). Methods Retrospective case series of six patients with HoFH treated with lomitapide in an Italian clinic.
Patrizia Suppressa, Chiara Coppola, Veronica Cocco, Sallyann O’Brien   +3 more
doaj   +1 more source

Inhibition of hepatic microsomal triglyceride transfer protein – a novel therapeutic option for treatment of homozygous familial hypercholesterolemia

Vascular Health and Risk Management, 2014
Alpo Vuorio,1,2 Matti J Tikkanen,3 Petri T Kovanen4 1Health Center Mehiläinen, Vantaa, Finland; 2Finnish Institute of Occupational Health, Lappeenranta, Finland; 3Heart and Lung Center, Helsinki University Central Hospital, Folkhälsan Research ...
Vuorio A, Tikkanen MJ, Kovanen PT
doaj