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The Dresden Apheresis Center – experience with LDL apheresis and immunoadsorption
Atherosclerosis Supplements, 2009The first apheresis center in former German Democratic Republic was established in Dresden November 1990 following the reunification of Germany. We here summarize the activities of this center to date. From the center's establishment until the end of July 2009 13,291 sessions of therapeutic apheresis have been performed.
Ulrich, Julius +4 more
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Treatment of Severe Hypercolesterolaemia by LDL-Apheresis
Biomaterials, Artificial Cells and Immobilization Biotechnology, 1991The most severe forms of hypercholesterolaemia scarcely respond to diet and conventional drugs administration and need, therefore, alternative treatments. Terapeutic Plasma Exchange demonstrated an improved survival of subjects with Familial Hypercholesterolaemia (FH) in spite of its limitations.
SCARPATO, NICOLA +6 more
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Comparison of different LDL apheresis methods
Expert Review of Cardiovascular Therapy, 2008This article presents the generally accepted indications for LDL apheresis treatment. The available LDL apheresis methods differ with respect to acute relative reductions of LDL cholesterol; mean values after the LDL apheresis treatments are not different. Serum triglycerides, HDL-cholesterol, and lipoprotein(a) are also acutely reduced.
Ulrich, Julius +5 more
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Applications of LDL-apheresis in nephrology
Clinical and Experimental Nephrology, 2008LDL-apheresis (LA) was originally used for familial hyperlipidemia, and then in Japan extended to use for the treatment of patients with peripheral arterial disease (PAD) and nephrotic syndrome due to steroid-resistant focal glomerular sclerosis (FGS). The reason why this treatment is applicable for these disorders is due to the fact that LA exerts its
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An update on LDL apheresis for nephrotic syndrome
Pediatric Nephrology, 2018Low-density lipoprotein (LDL) apheresis has been used increasingly in clinical practice for the treatment of renal diseases with nephrotic syndrome (NS), specifically focal segmental glomerulosclerosis (FSGS). Persistent hyperlipidemia for prolonged periods is nephrotoxic and leads to chronic progressive glomerular and tubulointerstitial injury ...
Rupesh Raina, Vinod Krishnappa
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LDL Apheresis and Inflammation – Implications for Atherosclerosis
Scandinavian Journal of Immunology, 2012AbstractLow‐density lipoprotein (LDL) apheresis is an extracorporeal treatment modality used in high‐risk patients when LDL cholesterol levels cannot be reduced adequately with medication. The treatment is highly effective, but could be affected by potential unwanted effects on pro‐ and anti‐inflammatory biomarkers.
A, Hovland +2 more
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Recommendations for the use of LDL apheresis
Atherosclerosis, 2008Plasma exchange has been shown to increase life-expectancy in homozygous familial hypercholesterolaemia (FH) but increasingly is being replaced by LDL apheresis. Several methods are now available for undertaking this procedure, which lowers LDL cholesterol and Lp(a) efficiently and safely when performed weekly or bi-weekly and causes only slight ...
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LDL Apheresis in Atherosclerotic Disease with Hyperlipidemia
ASAIO Journal, 1992Low density lipoprotein (LDL) apheresis was carried out in 28 atherosclerotic patients with clinical signs of poor peripheral circulation and abnormally high LDL levels. The LDL apheresis using extracorporeal adsorption with a dextran sulfate cellulose column (Liposorber, Kaneka, Japan) was done 10 times over 3 months.
S, Naganuma, T, Agishi, K, Ota
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Organization and Technical Problems of LDL-apheresis
The International Journal of Artificial Organs, 1993The Authors consider problems related to technique and organization of LDL-Apher-esis with respect to some particular aspects. They evaluate: a) Technical complexity of procedures both in devices to use and in staff preparation; b) Length of treatment which conditions the other fields of activity; c)
N, Scarpato +3 more
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Overview: Techniques and Indications of LDL-Apheresis
Biomaterials, Artificial Cells and Immobilization Biotechnology, 1991In recent years, LDL-apheresis has emerged to be an efficient treatment of hyperlipidemia in patients who do not respond sufficiently to diet and lipid lowering drugs. A survey of LDL lowering extracorporeal procedures is presented. Among them, to date 5 procedures have been used clinically on a routine basis: unselective plasma exchange, semi ...
T, Bosch, H J, Gurland
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