Results 71 to 80 of about 3,049 (238)
ReportsFamilial hypercholesterolemia, a genetic disorder marked by elevated low-density lipoprotein cholesterol (LDL-C), poses significant risks for premature atherosclerosis and cardiovascular diseases, particularly during pregnancy. One of the safe methods of
Milos Milincic +6 more
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American Journal of Preventive Cardiology, 2023 Therapeutic Area: ASCVD /CVD Risk Reduction Background: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by severely elevated low-density lipoprotein cholesterol (LDL-C) levels.
Albert Wiegman +15 more
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Frontiers in Pediatrics, 2020 Homozygous familial hypercholesterolemia (HoFH) is a rare inherited metabolic disorder, frequently leading to an early cardiovascular death if not adequately treated.
Matej Mlinaric +8 more
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PCSK9 Inhibitors: The Evolving Future
Health Science Reports, Volume 7, Issue 11, November 2024.ABSTRACT Introduction PCSK9 inhibitors are a novel class of medications that lower LDL cholesterol (LDL‐C) by increasing LDL receptor activity, promoting clearance of LDL‐C from the bloodstream. Over the years, PCSK9 inhibitors have been explored as adjunct therapies to statins or as monotherapy in high‐risk cardiovascular patients.
Bijay Mukesh Jeswani +5 more
wiley +1 more source
Pediatric Anesthesia, Volume 34, Issue 11, Page 1107-1118, November 2024.Abstract Domino liver transplantation and domino‐auxiliary partial orthotopic liver transplantation are emerging techniques that can expand the liver donor pool and provide hope for children with liver disease. The innovative technique of domino liver transplantation has emerged as a pioneering strategy, capitalizing on structurally preserved livers ...
Ahmed Uslu +3 more
wiley +1 more source
Treatment of Homozygous Familial Hypercholesterolemia With EvinacumabNovel Teaching Points
CJC Open, 2022 Patients with homozygous familial hypercholesterolemia (HoFH) have extremely elevated levels of low-density lipoprotein cholesterol (LDL-C), with premature atherosclerosis and aortic valve disease.
Natasha Jeraj, BSc +3 more
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Label Distribution Learning [PDF]
arXiv, 2014 Although multi-label learning can deal with many problems with label ambiguity, it does not fit some real applications well where the overall distribution of the importance of the labels matters. This paper proposes a novel learning paradigm named \emph{label distribution learning} (LDL) for such kind of applications.
arxiv
The giant low-density lipoproteins (LDL) accumulation in the multi-layer artery wall model [PDF]
arXiv, 2014 The mathematical, four-layer model of the LDL transport across the arterial wall including the sensitivity of the transport coefficients to the wall shear stress (WSS) is studied. In that model the advection-diffusion equations in porous media are used to determine the LDL concentration profiles in each layer of the arterial wall.
arxiv
Relation between the High Density Phase and the Very-High Density Phase of Amorphous Solid Water [PDF]
, 2004 It has been suggested that high-density amorphous (HDA) ice is a structurally arrested form of high-density liquid (HDL) water, while low-density amorphous (LDA) ice is a structurally arrested form of low-density liquid (LDL) water. Recent experiments and simulations have been interpreted to support the possibility of a second "distinct" high-density ...
arxiv +1 more source
In vivo metabolism of LDL subfractions in patients with heterozygous FH on statin therapy
Journal of Lipid Research, 2004 LDL can be subfractionated into buoyant (1.020–1.029 g/ml−1), intermediate (1.030–1.040 g/ml−1), and dense (1.041–1.066 g/ml−1) LDLs. We studied the rebound of these LDL-subfractions after LDL apheresis in seven patients with heterozygous familial ...
H.C. Geiss +4 more
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