Results 81 to 90 of about 195,293 (269)

Protein adsorption during LDL-apheresis: proteomic analysis [PDF]

Nephrology Dialysis Transplantation, 2008
The aim of our study was to investigate the clearance of functional proteins by different low-density lipoprotein-apheresis (LDL-A) methods with the help of proteomic analyses.Proteins were eluated from the different LDL-A columns and investigated with 2D electrophoresis combined with mass spectrometry methods.
Dihazi, Hassan, Koziolek, Michael Johann, Soellner, Tanja, Kahler, Elke, Klingel, Reinhard, Neuhoff, Rieke, Strutz, Frank M., Mueller, Georg Anton   +7 more
openaire   +3 more sources

Insulin resistance, overweight, and obesity in apheresis donors: A call to reevaluate their eligibility—A prospective cohort study

Transfusion, Volume 65, Issue 6, Page 1072-1082, June 2025.
Abstract Background Apheresis procedures and the infusion of acid‐citrate‐dextrose induce metabolic alterations that may influence glucose metabolism. Although insulin resistance (IR), overweight, and obesity are not exclusion criteria for blood donation, their impact during apheresis procedure and on post‐donation metabolic responses remains ...
Edgar Barrientos‐Galeana, Gabriela Chico‐Barba, Mari Cruz Tolentino‐Dolores, Emmanuel Fernández‐Sánchez, Rosa María Morales‐Hernández, Selene Barragán‐Montes, Maria de los Angeles Rosales‐López, Raymundo Rodríguez‐Jurado, Ángel Sebastián Quebrado‐Benítez, María‐Cristina Ramírez‐González, Heriberto López‐Martínez, Noemi Hernández‐Cruz, Jannyn Herrera‐Juárez, Karla Eugenia Bermúdez‐Ferro, Rodrigo Castillo‐Llanos   +14 more
wiley   +1 more source

Low-density lipoprotein cholesterol lowering therapies: what is on the horizon? [PDF]

, 2015
Elevated low-density lipoprotein cholesterol (LDL-C) levels are associated with an increased risk for cardiovascular disease (CVD). Statins have been the cornerstone of lipid therapy to lower LDL-C for the past two decades, but despite significant ...
Figueredo, M.D., Vincent M, Gadi, Ramprasad   +1 more
core   +1 more source

Enhancement of Statin Effects on Lipid Lowering and Reduction of Cardiovascular Risk Score by (−)‐Epicatechin in Proof‐of‐Concept Pilot Study

Clinical and Translational Science, Volume 18, Issue 5, May 2025.
ABSTRACT Statins play an instrumental role in reducing and managing atherosclerotic cardiovascular disease (ASCVD) but can be difficult to tolerate due to muscle‐associated side effects. There remains an unmet need for strategies that improve statin tolerance and synergize their effect on atherogenic lipids. (−)‐Epicatechin (Epi) is a natural flavonoid
Cameron K. Ormiston, Aryana Pazargadi, Ashley Rosander, Guillermo Ceballos, Francisco Villarreal, Pam R. Taub   +5 more
wiley   +1 more source

COMPARATIVE EFFECT OF APHERESIS vs ATORVASTATIN/APHERESIS ON MARKERS OF INFLAMMATION IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA [PDF]

Objective: Patients with Familial Hypercholesterolemia (FH) have increased cardiovascular events. Clinical trials have demonstrated that lowering circulating lipid levels by LDL-apheresis has beneficial effects on prognosis.
Bigazzi, Federico, Minichilli, Fabrizio, Puntoni, Mariarita, Sampietro, Tiziana, Sbrana, Francesco   +4 more
core  

Systematic review and network meta-analysis on the efficacy of evolocumab and other therapies for the management of lipid levels in hyperlipidemia [PDF]

, 2017
Background: The proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors evolocumab and alirocumab substantially reduce low‐density lipoprotein cholesterol (LDL‐C) when added to statin therapy in patients who need additional LDL‐C reduction ...
Bray, Sarah, Bridges, Ian, Cheng, Lung-I, Dent, Ricardo, Deshpande, Sohan, Forbes, Carol A., Gandra, Shravanthi R., Kleijnen, Jos, Ross, Janine, Sattar, Naveed, Stroes, Erik S.G., Toth, Peter P., Worth, Gavin M., Worthy, Gillian   +13 more
core   +1 more source

Freeze‐dried plasma: Hemostasis and biophysical analyses for damage control resuscitation

Transfusion, Volume 65, Issue S1, Page S250-S264, May 2025.
Abstract Background Effective hemorrhage protocols prioritize immediate hemostatic resuscitation to manage hemorrhagic shock. Prehospital resuscitation using blood products, such as whole blood or alternatively dried plasma in its absence, has the potential to improve outcomes in hemorrhagic shock patients.
Aron A. Shoara, Kanwal Singh, Henry T. Peng, Katy Moes, Jeong‐Ah Yoo, Sahar Sohrabipour, Sanewal Singh, Rex Huang, Peter Andrisani, Chengliang Wu, Katerina Pavenski, Paul Y. Kim, Bernardo Trigatti, Colin A. Kretz, Ori D. Rotstein, Shawn G. Rhind, Andrew N. Beckett   +16 more
wiley   +1 more source

コウテンセイ シケツ イジョウ オ ガッペイ シ low density lipoprotein アフェレーシス セコウジ オヨビ シキュウ ケイブ セイケンジ ニ シケツ コンナンナ セイキ シュッケツ オ キタシタ カゾクセイ コウコレステロール ケッショウ ガッペイ シキュウケイガン ノ イチレイ [PDF]

, 2015
今回我々は、家族性高コレステロール血症（FH）を合併し、low density lipoprotein（LDL）アフェレーシス後に不正性器出血を繰り返した臨床的に子宮頸癌と診断した症例を経験したので報告する。症例は49 歳、未経妊の女性。既往歴として、FH の他、心血管系疾患の術後治療として、ワーファリンとアスピリンを内服していた。LDL アフェレーシス後に、大量の不正性器出血を主訴に当院へ救急搬送された。腟鏡診では子宮腟部に明らかな腫瘍を認めなかったが、magnetic resonance ...
永瀬 智, 渡邉 憲和, 高橋 俊文   +2 more
core   +1 more source

The feasibility of monitoring trauma patients with a wireless, wearable Doppler ultrasound

Transfusion, Volume 65, Issue S1, Page S123-S130, May 2025.
Abstract Background Early detection of reduced stroke volume (SV) or cardiac output (CO) may expedite resuscitative interventions during traumatic hemorrhage; corrected carotid artery flow time (ccFT) has been proposed as a surrogate for SV during blood volume loss.
Luis Da Luz, Sarah Atwi, Lowyl Notario, Rachael Irvine, Diane Farah, Delaney Johnston, Jon‐Emile S. Kenny, Joseph K. Eibl, Dylan Pannell   +8 more
wiley   +1 more source

Low-density lipoprotein apheresis shows a rapid response to proteinuria due to C3 glomerulonephritis: a case report and literature review

Renal Replacement Therapy
Background C3 glomerulonephritis (C3GN) is a rare renal disorder caused by dysregulation of the alternative complement pathway, resulting in abnormal C3 activation and deposition.
Hideki Matsumura, Yuko Fujii, Tomoko Tanaka, Maki Kagitani, Akira Ashida   +4 more
doaj   +1 more source