Results 101 to 110 of about 127,223 (162)

OptiMo-LDLr: An Integrated In Silico Model with Enhanced Predictive Power for LDL Receptor Variants, Unraveling Hot Spot Pathogenic Residues. [PDF]

open access: yesAdv Sci (Weinh)
Larrea-Sebal A   +12 more
europepmc   +1 more source

Oxidized LDL receptors: a recent update

Current Opinion in Lipidology, 2023
Purpose of review LDL in its oxidized form, or ‘oxLDL’, is now generally acknowledged to be highly proatherogenic and to play a significant role in atherosclerotic plaque formation. Therefore, there has been increasing interest in understanding the significance of oxLDL and its receptors in different phases of atherosclerosis ...
Mohd Azeem, Khan   +7 more
openaire   +2 more sources

LDL receptor polymorphisms revisited

Blood, 2010
In this issue of Blood , Martinelli and colleagues describe that certain single-nucleotide polymorphisms in the LDL receptor gene independently associate with high plasma levels of coagulation factor VIII in patients with coronary artery disease.[1][1] In 1985, Drs M. S. Brown and J.
openaire   +2 more sources

LDL Receptor's β-Propeller Displaces LDL

Science, 2002
The low density lipoprotein receptor (LDLR) binds to lipoprotein extracellularly and releases it in the endosome. In his Perspective, Innerarity discusses new structural work (Rudenkoet al.) that shows that an interdomain interaction that occurs at low pH likely displaces ligand from the receptor in the endosome.
openaire   +1 more source

[LDL receptors].

Revue medicale de Bruxelles, 1991
The low density lipoprotein receptor removes the cholesterol-carrying lipoproteins from blood. When the activity of LDL receptors is reduced, as a result of genetic or acquired abnormalities, LDL increases in blood, resulting in atherosclerosis. Heterozygote familial hypercholesterolemia (one mutant gene) is characterized by a 50% reduction of LDL ...
openaire   +1 more source

LDL-receptor

2000
Opisan je značaj LDL-receptora u metabolizmu kolesterola te metoda protočne citometrije s pomoću koje se može dobiti uvid u relativnu aktivnost LDL-receptora na površini kultiviranih monocita.
Užarević, Branka   +1 more
openaire  

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