Results 111 to 120 of about 2,591,141 (428)
Measurement of total hepatic low density lipoprotein receptor levels in the hamster.
Journal of Lipid Research, 1993 The ability to measure the total concentration of low density lipoprotein (LDL) receptors in hepatic tissues is of crucial importance to understanding changes in hepatic cholesterol metabolism.
PG Cosgrove, BJ Gaynor, HJ Harwood, Jr
doaj
LDL: Line Distance Functions for Panoramic Localization [PDF]
arXiv, 2023 We introduce LDL, a fast and robust algorithm that localizes a panorama to a 3D map using line segments. LDL focuses on the sparse structural information of lines in the scene, which is robust to illumination changes and can potentially enable efficient computation.
arxiv
Three patients with homozygous familial hypercholesterolemia: Genomic sequencing and kindred analysis. [PDF]
, 2019 BackgroundHomozygous Familial Hypercholesterolemia (HoFH) is an inherited recessive condition associated with extremely high levels of low-density lipoprotein (LDL) cholesterol in affected individuals.
Balamir, Melek +15 more
core +1 more source
Thyroid hormone reduces cholesterol via a non-LDL receptor-mediated pathway.
Endocrinology, 2012 Although studies in vitro and in hypothyroid animals show that thyroid hormone can, under some circumstances, modulate the actions of low-density lipoprotein (LDL) receptors, the mechanisms responsible for thyroid hormone's lipid-lowering effects are not
I. Goldberg +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma +13 more
wiley +1 more source
, 2000 The peroxisome proliferator‐activated receptor γ (PPARγ) is a nuclear receptor that regulates fat-cell development and glucose homeostasis and is the molecular target of a class of insulin-sensitizing agents used for the management of type 2 diabetes ...
Andrew C. Li +5 more
semanticscholar +1 more source
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2012 Low-density lipoprotein (LDL) receptors are overexpressed in most neoplastic cell lines and provide a mechanism for the internalization and concentration of drug-laden nanoemulsions that bind to these receptors.
L. Pires +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu +13 more
wiley +1 more source
Quantification of apolipoprotein E receptors in human brain-derived cell lines by real-time polymerase chain reaction [PDF]
, 2004 Apolipoprotein (apo) E4 is a risk factor for Alzheimer's disease (AD) and other neurodegenerative diseases, compared to wild-type apoE3. The mechanism(s) is unknown.
Dingwall, C +4 more
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1995 Atherosclerotic lesions contain oxidized LDL (OxLDL), immunoglobulins, and immune-competent cells. Low levels of circulating autoantibodies against malondialdehyde (MDA)-modified lysine, an epitope of OxLDL, occur in several species, and immune complexes
W. Palinski, E. Miller, J. L. Witztum
semanticscholar +1 more source