Results 111 to 120 of about 127,223 (162)

LDL Receptor‐Related Proteins in Neurodevelopment

Traffic, 2003
Low‐density lipoprotein receptor‐related proteins (LRPs) are evolutionarily ancient cell‐surface receptors with diverse biological functions. All are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment.
Petra, May, Joachim, Herz
openaire   +2 more sources

Scavenger Receptors, Oxidized LDL, and Atherosclerosis

Annals of the New York Academy of Sciences, 2001
Abstract: Oxidized LDL (OxLDL) competes with oxidatively damaged and apoptotic cells for binding to mouse peritoneal macrophages, implying the presence of one or more common domains. However, the nature of the ligands involved has not been determined.
A, Boullier, D A, Bird, M K, Chang, E A, Dennis, P, Friedman, K, Gillotre-Taylor, S, Hörkkö, W, Palinski, O, Quehenberger, P, Shaw, D, Steinberg, V, Terpstra, J L, Witztum   +12 more
openaire   +2 more sources

LOWERING PLASMA CHOLESTEROL BY RAISING LDL RECEPTORS

Atherosclerosis Supplements, 1981
More than 93 per cent of the body's cholesterol is located in cells, where it performs vital structural and metabolic functions; only about 7 per cent circulates in plasma, where it predisposes to ...
M S, Brown, J L, Goldstein
openaire   +2 more sources

Determination of LDL Receptors on Cultured Lymphocytes Using Fluorescein-Labeled LDL

American Journal of Clinical Pathology, 1982
A rapid, sensitive procedure for the detection of LDL receptors on cell surface without using radioisotopes is described. Fluorescein-isothiocyanate (FITC) labeled LDL bound with cultured human lymphocytes, and the degree of that binding was compatible with that of 125 I-labeled LDL.
H, Sakai, H, Kaneshige, M, Endoh
openaire   +2 more sources

The LDL-Receptor Family

1998
Recently we described the specific inhibitory action of lactoferrin on chylomicron remnant (CR) uptake into the intact rat liver. Injection of lactoferrin but not transferrin (7 mg/100 g animal weight) together with radiolabelled CR inhibits in vivo uptake into liver by 50%. No inhibition of uptake into spleen was observed1.
M. Huettinger, M. Meilinger, Ch. Gschwentner, H. Lassmann   +3 more
openaire   +1 more source

Familial hypercholesterolaemia and LDL receptor mutations

Journal of Internal Medicine, 1992
Abstract. Inherited defects in the gene for the low density lipoprotein (LDL)‐receptor give rise to familial hypercholesterolaemia (FH), a disorder in which defective catabolism of LDL causes a marked increase in its concentration in plasma. As a result, there is excessive deposition of cholesterol in the arterial wall leading to accelerated ...
openaire   +2 more sources

LDL-receptor i hiperkolesterolemija

2003
Cilj je bio utvrditi postojanje i učestalost molekularnih promjena u genu za LDL-receptor u bolesnika s hiperkolesterolemijom. Ispitana je skupina od 249 bolesnika izabrana prema vrijednostima kolesterola većim od 4 mmol/L. Pretraživanje promotora i svih 18 eksona gena za LDL-receptor provedeno je PCR-SSCP metodom.
Zrinski-Topić, Renata, Gabela, Olga, Flogel, Mirna, Sertić, Jadranka, Stavljenić Rukavina, Ana   +4 more
openaire   +2 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Rujul Parikh
exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Victoria Metaxa, Elie Azoulay   +2 more
exaly