Results 231 to 240 of about 230,793 (312)

Tempol improves lipid profile and prevents left ventricular hypertrophy in LDL receptor gene knockout (LDLr-/-) mice on a high-fat diet

, 2017
Igor Cândido Viana Gonçalves, Cláudio Daniel Cerdeira, Eduardo Poletti Camara, José Antônio Dias Garcia, Maı́sa Ribeiro Pereira Lima Brigagão, Roberta Bessa Veloso Silva, Gérsika Bitencourt dos Santos   +6 more
openalex   +1 more source

The antagonist of P2Y11 receptor NF157 ameliorates oxidized LDL-induced vascular endothelial inflammation [PDF]

, 2019
Yun Kuang, Hui Liu, Siyu Guo, Yufei Wang, Huijuan Zhang, Yanxiang Qiao   +5 more
openalex   +1 more source

Peach Kernel Oil Modulates Lipid Metabolism Disorder in ApoEa CRISPR/Cas9 Gene‐Disrupted Zebrafish

Food Frontiers, EarlyView.
In this study, we used CRISPR/Cas9 gene editing technology to establish a lipid metabolism disorder model of ApoEa mutant zebrafish. We applied peach kernel oil to this model and studied the mechanism of peach kernel oil regulating lipid disorder in combination with transcriptomics.
Lei Xia, Yuemi Mo, Yuntian Duan, Hu Liang, Yulu Li, Wanruo Wan, Minghuang Luo, Qianhua Li, Xueni Wang, Qing Chen, Zhengcai Du, Xiaotao Hou, Fan Zhang, Jiagang Deng, Erwei Hao   +14 more
wiley   +1 more source

Sphingosine 1-phosphate receptor 1signaling in macrophages reduces atherosclerosis in LDL receptor-deficient mice. [PDF]

JCI Insight
Potì F, Scalera E, Feuerborn R, Fischer J, Arndt L, Varga G, Pardali E, Seidl MD, Fobker M, Liebisch G, Hesse B, Lukasz AH, Rossaint J, Kehrel BE, Rosenbauer F, Renné T, Christoffersen C, Simoni M, Burkhardt R, Nofer JR.   +19 more
europepmc   +1 more source

Loss of GPR40 in LDL receptor-deficient mice exacerbates high-fat diet-induced hyperlipidemia and nonalcoholic steatohepatitis. [PDF]

PLoS One, 2022
Lu Z, Li Y, Li AJ, Syn WK, Wank SA, Lopes-Virella MF, Huang Y.   +6 more
europepmc   +1 more source

Nutritional Value and Memory‐Improving Effects of Seven Major Nuts: A Comprehensive Study Using Network Pharmacology and In Vivo Assays

Food Frontiers, EarlyView.
This study highlights the memory‐enhancing effects of walnuts, almonds, and Torreya, with walnuts showing the strongest potential to improve cognitive function and delay brain aging. ABSTRACT This study explored the memory‐enhancing potential of seven commercially available nuts through nutritional profiling, metabolomics, network pharmacology, and ...
Jiamin Chen, Ben Niu, Ruiling Liu, Chaoyi Shen, Huizhi Chen, Mohamed A. Farag, Hangjun Chen, Qi Chen, Long Jin, Weijie Wu, Haiyan Gao   +10 more
wiley   +1 more source

Atorvastatin enhances LDL receptor-mediated LDL-C uptake and modulates PCSK9 protein expression in pancreatic β-cells. [PDF]

Islets
Zhang Z, Zheng H, Zhang L, Su P, Chen X, Xiang A, Yang J, Guan H, Fan J, Yu Q.   +9 more
europepmc   +1 more source

Sarpogrelate and atorvastatin synergistically ameliorate hyperlipidemia-induced aortic damage in LDL receptor deficient (LDL-R⁻/⁻) mice

, 2019
Zhipeng Zhang, Fan Yang, Rongmei Na, Hongyang Liu, Zuowei Pei   +4 more
openalex   +2 more sources

Liver LDL Receptor mRNA Expression Is Decreased in Human ApoB/CETP Double Transgenic Mice and Is Regulated by Diet as Well as the Cytokine Oncostatin M [PDF]

, 1997
Jingwen Liu, Y. Lynda Zhang, Michael Spence, Robert E. Vestal, Philip M. Wallace, David Grass   +5 more
openalex   +1 more source

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers, EarlyView.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
wiley   +1 more source