Replacement of saturated fatty acids with linoleic acid in western diet attenuates atherosclerosis in a mouse model with inducible ablation of hepatic LDL receptor. [PDF]
Sci Rep, 2023 Burr SD +4 more
europepmc +1 more source
Deletion of exon 15 of the LDL receptor gene is associated with a mild form of familial hypercholesterolemia. FH-Espoo. [PDF]
, 1993 Pekka Koivisto +5 more
openalex +1 more source
Recycling the LDL receptor to combat atherosclerosis
Aging, 2018 Jan Albert Kuivenhoven +2 more
openaire +4 more sources
ESC Heart Failure, EarlyView.Abstract Aims Dapagliflozin (DAPA), a sodium‐glucose co‐transporter 2 inhibitor, has been shown to reduce cardiovascular mortality among patients with chronic heart failure. We aimed to evaluate the impact on a worsening renal function (WRF) by adding DAPA as compared to standard decongestive therapy with loop diuretics alone.
Shodai Kawanami +11 more
wiley +1 more source
Protein kinase C activation stabilizes LDL receptor mRNA via the JNK pathway in HepG2 cells*[S]
Journal of Lipid Research, 2009 LDL is the most abundant cholesterol transport vehicle in plasma and a major prognostic indicator of atherosclerosis. Hepatic LDL receptors limit circulating LDL levels, since cholesterol internalized by the liver can be excreted.
Noelle B. Vargas +3 more
doaj
Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor. [PDF]
Sci Transl Med, 2022 Smith GA +16 more
europepmc +1 more source
Response to HMG CoA reductase inhibitors in heterozygous familial hypercholesterolemia due to the 10-kb deletion ("French Canadian mutation") of the LDL receptor gene. [PDF]
, 1994 Lala Karayan +7 more
openalex +1 more source
Protein deglycosylation can drastically affect the cellular uptake [PDF]
, 2019 Ghazaryan, A. +2 more
core +2 more sources
ESC Heart Failure, EarlyView.Abstract Background Heart failure (HF) is a risk factor for ischemic stroke. Cognitive impairment is very common in HF and stroke patients. Patients with HF have higher risk of developing dementia. However, there are limited studies investigating the characteristics, in‐hospital mortality and complications of stroke patients with both HF and dementia ...
Lijun Zuo +6 more
wiley +1 more source
Journal of Lipid Research, 1997 To search for unique mutations in the apolipoprotein B (apoB) gene that disrupt the binding of LDL to its receptor and cause hypercholesterolemia, we examined more than 800 patients with high LDL cholesterol levels and/or coronary artery disease (CAD ...
E H Ludwig +8 more
doaj