alpha-2 Macroglobulin receptor/Ldl receptor-related protein(Lrp)-dependent internalization of the urokinase receptor. [PDF]
Massimo Conese+8 more
openalex +1 more source
Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial
Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in patients with ...
Zhuoshan Huang+18 more
wiley +1 more source
Lectin-type oxidized LDL receptor-1 as a potential therapeutic target for cerebral cavernous malformations treatment. [PDF]
Ashok K+9 more
europepmc +1 more source
Atherosclerotic plaque regression in homozygous familial hypercholesterolaemia: a case report of a long-term lipid-lowering therapy involving LDL-receptor-independent mechanisms. [PDF]
Khoury E+4 more
europepmc +1 more source
Association of ventricular–arterial coupling with heart failure (HF) biomarkers in the STANISLAS cohort. MMP, matrix metalloproteinase; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide. Aims Impaired left ventricular–arterial coupling (VAC) has been shown to correlate with worse prognosis in cardiac diseases and heart failure (HF).
Hannes Holm+12 more
wiley +1 more source
Apolipoprotein O modulates cholesterol metabolism via NRF2/CYB5R3 independent of LDL receptor. [PDF]
Chen J+10 more
europepmc +1 more source
Increased LDL receptor by SREBP2 or SREBP2-induced lncRNA LDLR-AS promotes triglyceride accumulation in fish. [PDF]
Cao X+5 more
europepmc +1 more source
The analysis workflow, findings and potential clinical consequences of iron deficiency in heart failure (HF). From 881 patients with worsening HF, whole blood transcriptome was analysed using the Affymetrix Human Transcriptome Array (HTA) 2.0. Subjects were stratified according to their transferrin saturation (TSAT) levels as iron‐deficient (TSAT <20%)
Niels Grote Beverborg+17 more
wiley +1 more source