Results 31 to 40 of about 2,605,698 (332)
Drug Delivery, 2020 Presently, a combination of chemotherapy, radiotherapy, thermotherapy, and other treatments has become a hot topic of research for the treatment of cancer, especially lung cancer.
Yan Shen +7 more
doaj +1 more source
High bone density due to a mutation in LDL-receptor-related protein 5.
New England Journal of Medicine, 2002 BACKGROUND Osteoporosis is a major public health problem of largely unknown cause. Loss-of-function mutations in the gene for low-density lipoprotein receptor-related protein 5 (LRP5), which acts in the Wnt signaling pathway, have been shown to cause ...
L. Boyden +8 more
semanticscholar +1 more source
Heparan sulfate proteoglycans present PCSK9 to the LDL receptor
Nature Communications, 2017 Coronary artery disease is the main cause of death worldwide and accelerated by increased plasma levels of cholesterol-rich low-density lipoprotein particles (LDL).
Camilla Gustafsen +13 more
semanticscholar +1 more source
СОХРАНЕНИЕ РЕЦЕПТОРОВ ЛПНП — НОВЫЙ ПОДХОД К ТЕРАПИИ ГИПЕРЛИПИДЕМИИ
Архивъ внутренней медицины, 2013 LDL receptor plays a key role in the metabolism of LDL cholesterol. It have been shown that proprotein convertase subtlisin/kexin type 9 is essential for post-transcriptional regulatation of the cell surface expression of the LDL receptor by ...
С. С. Бажан
doaj +1 more source
Structural Properties of High and Low Density Water in a Supercooled Aqueous Solution of Salt [PDF]
J. Phys. Chem. B 115(6), 1461-1468 (2011), 2011 We consider and compare the structural properties of bulk TIP4P water and of a sodium chloride aqueous solution in TIP4P water with concentration c = 0.67 mol/kg, in the metastable supercooled region. In a previous paper [D. Corradini, M. Rovere and P. Gallo, J. Chem. Phys.
arxiv +1 more source
Label Distribution Learning from Logical Label [PDF]
arXiv, 2023 Label distribution learning (LDL) is an effective method to predict the label description degree (a.k.a. label distribution) of a sample. However, annotating label distribution (LD) for training samples is extremely costly. So recent studies often first use label enhancement (LE) to generate the estimated label distribution from the logical label and ...
arxiv
Hepatitis C virus relies on lipoproteins for its life cycle [PDF]
, 2016 Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino +5 more
core +1 more source
Lipoprotein assembly and function in an evolutionary perspective
Biomolecular Concepts, 2010 Circulatory fat transport in animals relies on members of the large lipid transfer protein (LLTP) superfamily, including mammalian apolipoprotein B (apoB) and insect apolipophorin II/I (apoLp-II/I).
Van der Horst Dick J., Rodenburg Kees W.
doaj +1 more source
Exploiting Multi-Label Correlation in Label Distribution Learning [PDF]
arXiv, 2023 Label Distribution Learning (LDL) is a novel machine learning paradigm that assigns label distribution to each instance. Many LDL methods proposed to leverage label correlation in the learning process to solve the exponential-sized output space; among these, many exploited the low-rank structure of label distribution to capture label correlation ...
arxiv
Unraveling liquid polymorphism in silicon driven out-of-equilibrium [PDF]
J. Chem. Phys. 153, 054502 (2020), 2020 Using nonequilibrium molecular dynamics (NEMD) simulations, we study the properties of supercooled liquids of Si under shear at T=1060K over a range of densities encompassing the low-density liquid (LDL) and high-density liquid (HDL) forms. This enables us to generate nonequilibrium steady-states of the LDL and HDL polymorphs, that remain stabilized in
arxiv +1 more source