Results 61 to 70 of about 2,605,698 (332)

Bidirectional Loss Function for Label Enhancement and Distribution Learning [PDF]

arXiv, 2020
Label distribution learning (LDL) is an interpretable and general learning paradigm that has been applied in many real-world applications. In contrast to the simple logical vector in single-label learning (SLL) and multi-label learning (MLL), LDL assigns labels with a description degree to each instance. In practice, two challenges exist in LDL, namely,
arxiv  

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT, Bednar MM, Bellosta S, Buttrum SM, Buyon JP, Calara F, Calderon TM, Diacovo TG, Giroux LM, Jukema JW, Kim JA, Kimura M, Laufs U, Laws KH, Lehr H-A, Marcus AJ, Notabartolo A, Olstrowsky L, Pons F, Ruf A, Smalley DM, Stragliotto E, Sugiyama S, Weber C, Weber C, Weber C, Yeagle PL, Yeo EL, Yue TL   +28 more
core   +1 more source

LDL: A Defense for Label-Based Membership Inference Attacks [PDF]

arXiv, 2022
The data used to train deep neural network (DNN) models in applications such as healthcare and finance typically contain sensitive information. A DNN model may suffer from overfitting. Overfitted models have been shown to be susceptible to query-based attacks such as membership inference attacks (MIAs). MIAs aim to determine whether a sample belongs to
arxiv  

LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies.

Physiological Reviews, 2008
The LDL receptor-related protein (originally called LRP, but now referred to as LRP1) is a large endocytic receptor that is widely expressed in several tissues.
A. Lillis, Lauren B Van Duyn, J. Murphy-Ullrich, D. Strickland   +3 more
semanticscholar   +1 more source

Regulation of low density lipoprotein receptor gene expression in HepG2 and Caco2 cells by palmitate, oleate, and 25-hydroxycholesterol

Journal of Lipid Research, 1995
Our in vivo studies in mice have shown that LDL-receptor gene expression is regulated differently in both liver and intestine by dietary cholesterol and dietary saturated fat.
R A Srivastava, H Ito, M Hess, N Srivastava, G Schonfeld   +4 more
doaj  

Algebraic study of receptor-ligand systems: a dose-response analysis [PDF]

arXiv, 2022
The study of a receptor-ligand system generally relies on the analysis of its dose-response (or concentration-effect) curve, which quantifies the relation between ligand concentration and the biological effect (or cellular response) induced when binding its specific cell surface receptor.
arxiv  

Polyphenols Stimulate AMP-Activated Protein Kinase, Lower Lipids, and Inhibit Accelerated Atherosclerosis in Diabetic LDL Receptor–Deficient Mice

Diabetes, 2006
Because polyphenols may have beneficial effects on dyslipidemia, which accelerates atherosclerosis in diabetes, we examined the effect of polyphenols on hepatocellular AMP-activated protein kinase (AMPK) activity and lipid levels, as well as ...
Mengwei Zang, Shanqin Xu, Karlene A. Maitland-Toolan, A. Zuccollo, X. Hou, B. Jiang, M. Wierzbicki, T. Verbeuren, R. Cohen   +8 more
semanticscholar   +1 more source

Quantification of apolipoprotein E receptors in human brain-derived cell lines by real-time polymerase chain reaction [PDF]

, 2004
Apolipoprotein (apo) E4 is a risk factor for Alzheimer's disease (AD) and other neurodegenerative diseases, compared to wild-type apoE3. The mechanism(s) is unknown.
Dingwall, C, Everett, DM, Murdock, PR, Owen, JS, Thilakawardhana, S   +4 more
core   +1 more source

Small dense low density lipoprotein has increased affinity for LDL receptor-independent cell surface binding sites: a potential mechanism for increased atherogenicity1

Journal of Lipid Research, 1998
Small dense low density lipoprotein (LDL) particles have altered apolipoprotein (apo) B conformation and lowered affinity for the LDL receptor (J. Biol. Chem. 1994. 269: 511–519).
Narmer F. Galeano, Maysoon Al-Haideri, Fannie Keyserman, Steven C. Rumsey, Richard J. Deckelbaum   +4 more
doaj  

Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study [PDF]

, 2015
Objectives The interleukin-6 receptor (IL-6R) blocker tocilizumab (TCZ) reduces inflammatory disease activity in rheumatoid arthritis (RA) but elevates lipid concentrations in some patients.
Bathon, Joan M., Beaulieu, Andre D., Carlson, Timothy H., Codding, Christine E., Delles, Christian, Giles, Jon T., Lee, Janet S., McInnes, Iain B., Salmon, Jane E., Sattar, Naveed, Thompson, Liz   +10 more
core   +1 more source