Results 81 to 90 of about 2,605,698 (332)
Mitogenic stimulation alters the regulation of LDL receptor gene expression in human lymphocytes.
Journal of Lipid Research, 1990 To address the possibility that influences other than ambient cholesterol concentrations regulate low density lipoprotein (LDL) receptor expression, the effect of mitogenic activation on the levels of LDL receptor mRNA in human lymphocytes was examined ...
JA Cuthbert, PE Lipsky
doaj
Insights into regulation of lipoprotein receptors in human mesangial cells: The effects of inflammatory cytokines and calcium channel blockers. [PDF]
, 2001 The involvement of abnormal lipid metabolism in the progression of renal disease and the pathogenesis of chronic graft dysfunction is generally accepted.
Ruan, Xiong Zhong
core
Measurement of total hepatic low density lipoprotein receptor levels in the hamster.
Journal of Lipid Research, 1993 The ability to measure the total concentration of low density lipoprotein (LDL) receptors in hepatic tissues is of crucial importance to understanding changes in hepatic cholesterol metabolism.
PG Cosgrove, BJ Gaynor, HJ Harwood, Jr
doaj
, 2000 The peroxisome proliferator‐activated receptor γ (PPARγ) is a nuclear receptor that regulates fat-cell development and glucose homeostasis and is the molecular target of a class of insulin-sensitizing agents used for the management of type 2 diabetes ...
Andrew C. Li +5 more
semanticscholar +1 more source
Thyroid hormone reduces cholesterol via a non-LDL receptor-mediated pathway.
Endocrinology, 2012 Although studies in vitro and in hypothyroid animals show that thyroid hormone can, under some circumstances, modulate the actions of low-density lipoprotein (LDL) receptors, the mechanisms responsible for thyroid hormone's lipid-lowering effects are not
I. Goldberg +6 more
semanticscholar +1 more source
Endocytosis of the ASGP receptor H1 is reduced by mutation of tyrosine-5 but still occurs via coated pits [PDF]
, 1991 The clustering of plasma membrane receptors in clathrin-coated pits depends on determinants within their cytoplasmic domains. In several cases, individual tyrosine residues were shown to be necessary for rapid internalization.
Fuhrer, C., Geffen, I., Spiess, M.
core +3 more sources
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2012 Low-density lipoprotein (LDL) receptors are overexpressed in most neoplastic cell lines and provide a mechanism for the internalization and concentration of drug-laden nanoemulsions that bind to these receptors.
L. Pires +6 more
semanticscholar +1 more source
Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]
, 1999 Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Alvarez C +27 more
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1995 Atherosclerotic lesions contain oxidized LDL (OxLDL), immunoglobulins, and immune-competent cells. Low levels of circulating autoantibodies against malondialdehyde (MDA)-modified lysine, an epitope of OxLDL, occur in several species, and immune complexes
W. Palinski, E. Miller, J. L. Witztum
semanticscholar +1 more source
Competitive uptake of porphyrin and LDL via the LDL receptor in glioma cell lines: flow cytometric analysis [PDF]
, 2001 We examined the simultaneous uptake of porphyrin and (LDL) by four established cell lines of glioma and normal ®broblastsusing ¯ow cytometry (FCM). The results indicated porphyrin and LDL showed competitive conjugation with the LDL receptor.These results
Matsumura Akira +8 more
core +1 more source