Results 161 to 170 of about 27,943 (287)

The Effect of Single Level and Multilevel Cervical Fusion on Adjacent Segment Motion: A Biomechanical Analysis

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background Cervical arthrodesis is a common surgical technique utilized to treat many cervical spinal pathologies. The risk of re‐operation due to symptomatic adjacent segment disease (ASD) remains steady, and the cause of ASD, whether rigid fixation or disease progression, remains unknown.
Kyle W. Morse, Kathleen N. Meyers, Patrick F. O'Leary, Timothy M. Wright, Darren R. Lebl   +4 more
wiley   +1 more source

Ligand Drift Rate Descriptor in Receptor Pocket: Molecular Docking Sampling for Differentiating Partial Agonists in Nuclear Receptors. [PDF]

J Chem Inf Model
Lin YT, Shih YT.
europepmc   +1 more source

Antitumor Activity of Combined Topoisomerase Inhibition and FLASH Radiotherapy in Head and Neck Carcinoma Biomodels

MedComm, Volume 7, Issue 9, September 2026.
We report a proof‐of‐concept combination of topoisomerase inhibition and FLASH radiotherapy showing enhanced antitumor activity in head and neck carcinoma biomodels, supporting further investigation of this strategy in more clinically representative models and treatment settings. ABSTRACT Locally advanced head and neck carcinoma remains associated with
Patrizia Sarogni, Nicoletta Brindani, Valentina Frusca, Melissa Santi, Andrea Cavalieri, Mariagrazia Celentano, Michele Menicagli, Andrea Marranci, Andrea Ghelli Luserna di Rorà, Federico Purificato, Michela Nigro, Noemi Giannini, Alessandra Gonnelli, Giovanni Gadducci, Fabio Di Martino, Fabiola Paiar, Marco De Vivo, Valerio Voliani   +17 more
wiley   +1 more source

Radiotherapy Technique Determines the Magnitude and Persistence of T-Lymphocyte DNA Damage. [PDF]

Cancers (Basel)
Kocsis ZS, Ágoston P, Farkas G, Székely G, Sándor GO, Jorgo K, Gesztesi L, Major T, Pesznyák C, Herein A, Stelczer G, Mihály D, Fröhlich G, Takácsi-Nagy Z, Polgár C, Jurányi Z.   +15 more
europepmc   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Beyond Intrinsic Limits: Polarization-Sensitive Carrier Dynamics Amplify Subtle Intrinsic Optical Anisotropy into Giant Linear Dichroism. [PDF]

Adv Mater
Zeng D, Zhang S, Shen X, Gao P, Li R, Hu W.   +5 more
europepmc   +1 more source

Impact of millimeter‐scale target motion on the precision of spatially fractionated radiation therapy using proton minibeams

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Background While pencil beam scanning (PBS) with motion mitigation such as re‐scanning, breath hold, or gating is well established for treating moving targets in clinical practice, the precision for Spatially Fractionated Radiation Therapy (SFRT) using proton minibeams introduces presents a unique challenge.
Oxana Actis, Cristian Fernandez‐Palomo, Verdiana Trappetti, Michele Togno, Paolo Pellicioli, Dominic Leiser, David Meer, Valentin Djonov   +7 more
wiley   +1 more source

Evaluating Risk Factors Associating With Late Recurrence After Low-Dose-Rate Brachytherapy for Prostate Cancer Using Machine Learning. [PDF]

Prostate
Onishi K, Nakahama T, Nakai Y, Tachibana A, Oda Y, Tomizawa M, Morizawa Y, Hori S, Gotoh D, Miyake M, Asakawa I, Yamaki K, Isohashi F, Fujimoto K, Tanaka N.   +14 more
europepmc   +1 more source

Robust optimization of catheter positions and dwell times for HDR prostate brachytherapy

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Background HDR prostate brachytherapy plans are sensitive to catheter placement uncertainty, as discrepancies between planned and delivered catheter positions can degrade target coverage and increase organ at risk dose. Current inverse planning methods optimize dwell times for a fixed implant geometry and do not account for geometric ...
Joseph B. Schulz, Bryan P. Bednarz, John M. Floberg, Jordan M. Slagowski   +3 more
wiley   +1 more source

Radiotherapy in Squamous Cell Carcinoma of the Lip: A Systematic Review of Reported Practices, Clinical Outcomes, and Gaps in Consensus. [PDF]

J Clin Med
Ciobănescu O, Crișan AE, Bălan RM, Pătrașcu V, Crișan AN, Dumitrescu CI, Moraru MC, Măceș S, Popescu M, Dumitrescu D.   +9 more
europepmc   +1 more source