The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Peter Orebech, Fred Bossleman, Jes Bjarup, David Callies, Martin Chanock and Hanne Petersen, The Role of Customary Law in Sustainable Development (Cambridge: Cambridge University Press, 2005) - Book Review [PDF]
Law, Environment and Development Journal, 2007 Reviewed by Roopa Madhav, LEAD Journal
doaj
When Patent Foramen Ovale (PFO) Can Cause Trouble-A Misplacement of Pacemaker Lead Into the Left Ventricle. [PDF]
Case Rep CardiolHelal A, Antoun I, El-Din M, Farooq M.
europepmc +1 more source
Laser‐Induced Dehalogenation for Direct Writing Stable, Thermally Robust Patterned Arrays of Lead Halide Perovskite Nanocrystals [PDF]
Duankai Wu +8 more
openalex +1 more source
Differential Androgen Deprivation Therapies with Anti-androgens Casodex/Bicalutamide or MDV3100/Enzalutamide versus Anti-androgen Receptor ASC-J9® Lead to Promotion versus Suppression of Prostate Cancer Metastasis [PDF]
, 2013 Tzu‐Hua Lin +9 more
openalex +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Blood-Based Lead Biomarkers and Sarcopenia Indicators in Older Adults. [PDF]
J Cachexia Sarcopenia MuscleKoni A +15 more
europepmc +1 more source
How to Lead the Board of Directors to a Sustainable Development of Business with the CSR Committees [PDF]
, 2019 Francesca Gennari
openalex +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source