Results 41 to 50 of about 14,838,699 (302)
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
A polyherbal formulation mainly composed of Hibiscus sabdariffa and Aloe barbadensis commonly patronized by some staff and students of a College Hospital in Ibadan, Nigeria was evaluated for its toxicity status and bioactive constituents.
O.M. Ighodaro +4 more
doaj +1 more source
Magnetization of small lead particles
The magnetization of an ensemble of isolated lead grains of sizes ranging from below 6 nm to 1000 nm is measured. A sharp disappearance of Meissner effect with lowering of the grain size is observed for the smaller grains. This is a direct observation by
A. Frydman +8 more
core +2 more sources
The development of antibody therapeutics relies on animal models that accurately recapitulate disease biology. Syngeneic mouse models are increasingly used with new molecules to capture the biology of complex cancers and disease states, and to provide ...
Feng Wang +17 more
doaj +1 more source
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait +23 more
wiley +1 more source
Creating a more strategic small molecule biophysical hit characterization workflow
To confirm target engagement of hits from our high-throughput screening efforts, we ran biophysical assays on several hundreds of hits from 15 different high-throughput screening campaigns.
Christopher Fotsch +11 more
doaj +1 more source
Current Sensorless Control Algorithm for Single-Phase Three-Level NPC Inverter
The current measurement is becoming a challenging task in power converters operating at high switching frequencies, moreover traditional control system requires two control loops - first (slow) regulates DC-link voltage, second (fast) controls the shape ...
Suzdalenko Alexander +2 more
doaj +1 more source
Time-frequency synchronization plays an important role in the construction of solar radio telescopes (such as heliograph and interferometry). In the development of a synchronization system, time-frequency signal is divided and transmitted to each antenna
Yuqing Liu +5 more
doaj +1 more source
Opposite momenta lead to opposite directions [PDF]
When a particle decays into two fragments, the wavefunctions of the latter are spherical shells with expanding radii. In spite of this spherical symmetry, the two particles can be detected only in opposite directions.Comment: 3 pages LaTeX, submitted to ...
Peres, Asher
core +2 more sources
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source

