Results 51 to 60 of about 15,018,893 (299)

Design and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models

open access: yesmAbs, 2020
The development of antibody therapeutics relies on animal models that accurately recapitulate disease biology. Syngeneic mouse models are increasingly used with new molecules to capture the biology of complex cancers and disease states, and to provide ...
Feng Wang   +17 more
doaj   +1 more source

Performance Comparison of Power Divider and Fiber Splitter in the Fiber-Based Frequency Transmission System of Solar Radio Observation

open access: yesIEEE Access, 2021
Time-frequency synchronization plays an important role in the construction of solar radio telescopes (such as heliograph and interferometry). In the development of a synchronization system, time-frequency signal is divided and transmitted to each antenna
Yuqing Liu   +5 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Current Sensorless Control Algorithm for Single-Phase Three-Level NPC Inverter

open access: yesElectrical, Control and Communication Engineering, 2014
The current measurement is becoming a challenging task in power converters operating at high switching frequencies, moreover traditional control system requires two control loops - first (slow) regulates DC-link voltage, second (fast) controls the shape ...
Suzdalenko Alexander   +2 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Lead Poisoning Thresholds and Triggers [PDF]

open access: yes, 2017
Lead poisoning remains a significant problem in the United States, especially in cities like Buffalo with old housing stock and concentrated poverty.
Hains, Adam
core   +1 more source

A generalized Caroli formula for transmission coefficient with lead-lead coupling

open access: yes, 2012
We present a generalized transmission coefficient formula for the lead-junction-lead system, in which interaction between the leads has been taken into account.
Agarwalla, Bijay Kumar   +2 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Youth Lead the Change: Participatory Budgeting [PDF]

open access: yes, 2017
This evaluation report examines the Youth Lead the Change process in its third year, drawing on qualitative and quantitative data from a variety of sources.
Augsberger, Astraea   +4 more
core   +2 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

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