Results 51 to 60 of about 275,648 (287)

Laser-driven Sisyphus cooling in an optical dipole trap

open access: yes, 2011
We propose a novel Sisyphus cooling scheme for atoms confined in a far off resonance optical dipole trap. Utilizing the differential trap-induced AC Stark shift, two electronic levels of the atom are resonantly coupled by a cooling laser preferentially ...
Gupta, Subhadeep, Ivanov, Vladyslav V.
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Analysis of ice climber sport performance during competition [PDF]

open access: yesFizička Kultura, 2018
Sport discipline ice climbing was built on the reputation of climbing frozen waterfalls and can be defined as a unique discipline under the International Climbing and Mountaineering Federation (UIAA) in artificial, prescribed conditions, and according to
Manovski Katarina   +5 more
doaj  

When the going gets rough – studying the effect of surface roughness on the adhesive abilities of tree frogs [PDF]

open access: yes, 2016
Tree frogs need to adhere to surfaces of various roughnesses in their natural habitats; these include bark, leaves and rocks. Rough surfaces can alter the effectiveness of their toe pads, due to factors such as a change of real contact area and abrasion
Barnes, W. Jon P.   +4 more
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Assessing the Impact of Neuromuscular Electrical Stimulation-Based Fingerboard Training versus Conventional Fingerboard Training on Finger Flexor Endurance in Intermediate to Advanced Sports Climbers: A Randomized Controlled Study

open access: yesSensors
Competitive climbers engage in highly structured training regimens to achieve peak performance levels, with efficient time management as a critical aspect.
Carlo Dindorf   +8 more
doaj   +1 more source

Accumulation and response to stress in climbing perch (Anabas testudineus) on exposure to high concentrations of lead and cadmium in water

open access: yesThe European Zoological Journal, 2022
Dans cette étude, le plomb (Pb) et le cadmium (Cd) ont été utilisés comme facteurs de stress chimiques. Des A. testudineus sains ont été exposés au Pb (20, 30 et 40 mg/L) et au Cd (3, 5 et 10 mg/L) pendant 7, 14, 21 et 28 jours pour évaluer la réponse de A. testudineus provoquée par ces métaux.
Dang Nguyen Nha Khanh   +8 more
openaire   +2 more sources

Directed enzyme evolution: climbing fitness peaks one amino acid at a time [PDF]

open access: yes, 2009
Directed evolution can generate a remarkable range of new enzyme properties. Alternate substrate specificities and reaction selectivities are readily accessible in enzymes from families that are naturally functionally diverse.
Arnold, Frances H., Tracewell, Cara A.
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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