Results 51 to 60 of about 2,290,510 (294)

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Identification of pyrazolopyridazinones as PDEδ inhibitors

open access: yesNature Communications, 2016
PDEδ is a widely expressed factor that sustains the spatial organization and signalling of Ras family proteins. Here the authors describe the activity of Deltazinone 1, a new highly selective PDEδ inhibitor of KRAS-dependent cancer cell growth with low ...
Björn Papke   +16 more
doaj   +1 more source

Adapting data management education to support clinical research projects in an academic medical center

open access: yesJournal of the Medical Library Association, 2019
Background: Librarians and researchers alike have long identified research data management (RDM) training as a need in biomedical research. Despite the wealth of libraries offering RDM education to their communities, clinical research is an area that has
Kevin B. Read
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

FP-tree and COFI Based Approach for Mining of Multiple Level Association Rules in Large Databases

open access: yes, 2010
In recent years, discovery of association rules among itemsets in a large database has been described as an important database-mining problem. The problem of discovering association rules has received considerable research attention and several ...
Kumar, Parveen   +2 more
core   +1 more source

Differential analysis of biological networks [PDF]

open access: yes, 2015
In cancer research, the comparison of gene expression or DNA methylation networks inferred from healthy controls and patients can lead to the discovery of biological pathways associated to the disease.
Montana, Giovanni   +2 more
core   +2 more sources

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior   +7 more
wiley   +1 more source

An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters

open access: yesFrontiers in Pharmacology, 2021
The solute carrier (SLC) superfamily represents the biggest family of transporters with important roles in health and disease. Despite being attractive and druggable targets, the majority of SLCs remains understudied. One major hurdle in research on SLCs
Vojtech Dvorak   +32 more
doaj   +1 more source

Learning About Something Means Becoming Wiser: The Platonic Dialogue as a Paradigmatic Model for Writing Center Practice [PDF]

open access: yes, 2017
As our discipline’s scholars, we must recognize that ours is a history “that is best recognized as an always incomplete narrative” and continue to delve into the past as we seek to inform our future (Lerner 25).
Raign, Kathryn
core   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

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