Results 161 to 170 of about 415,916 (299)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Lead-time-continuous statistical postprocessing of ensemble weather forecasts

open access: yes
Numerical weather prediction (NWP) ensembles often exhibit biases and errors in dispersion, so they need some form of post processing to yield sharp and well-calibrated probabilistic predictions.
JB Wessel (21964409)   +2 more
core  

User-driven innovation in the food industry : can mainstream users compete with lead users?

open access: yes, 2014
Summary This case study aims to explore the lead user phenomenon, more specifically the ideas these users generate in comparison to mainstream users. We use the case of healthy food to test existing theory.
Herland, Hanne Sofie, Giladi, Iris
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Disabled persons as lead users in product innovation: a literature overview

open access: yes, 2014
Lead users can be a valuable source for innovation. They are capable of detecting and experiencing needs before the general market does, and are willing to innovate because they can gain significant benefits if their needs are fulfilled.
De Couvreur, Lieven   +3 more
core  

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