Results 121 to 130 of about 3,515,275 (403)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Experiences of managerial accountability in Ethiopia’s primary healthcare system: a qualitative study

BMC Family Practice, 2020
Background Despite calls for improved accountability in global health systems, and a set of clear and consistent theoretical accountability frameworks, empirical descriptions of how accountability is experienced and enacted in low- and middle- income ...
Netsanet Fetene, Akshar Patel, Tibebu Benyam, Assefa Ayde, Mayur M. Desai, Leslie Curry, Erika Linnander   +6 more
doaj   +1 more source

Research Leadership Flow Determinants and the Role of Proximity in Research Collaborations Networks [PDF]

arXiv, 2019
Characterizing the leadership in research is important to revealing the interaction pattern and organizational structure through research collaboration. This research defines the leadership role based on the corresponding author's affiliation, and presents, the first quantitative research on the factors and evolution of five proximity dimensions ...
arxiv  

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

An Exploration of Rotating Leadership in a Knowledge Building Community [PDF]

arXiv, 2015
This study aims to investigate the COINs concept of rotating leadership within a Knowledge Building context. Individual and group level leadership patterns in a grade 4 science class were explored through temporal visualization of betweenness centrality.
arxiv  

ANALISIS PENGARUH GAYA KEPEMIMPINAN TERHADAP KINERJA PEGAWAI DI KANTOR SOSIAL DAN KESEJAHTERAAN RAKYAT KABUPATEN MALANG [PDF]

, 2007
Research is survey on the permanent employes in the social and people welfare office of malang regency entitled analysis on the effect of leadership style on Employees, performance in the social and people welfare office of malang regency.
MIATUN, MIATUN
core  

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Attributes of Embodied Leadership: A beginning in the next chapter of leadership development [PDF]

, 2015
Research and guidance on leadership behaviour has been documented throughout history, from the epics to more recent leadership theories, evolved over the last century. Why then, when there is so much research and advice available are leaders still making
Bass, Blair, Butterfield, Camenisch, Cardona, Copperider, Crossan, Davidson, Davidson, Davidson, Derue, Farber, Fry, Gehring, Goleman, Harung, Hede, Kriger, Kupers, Ladkin, Lutz, Meyer, Rarick, Scharmer, Seters, Sice, Thompson, Thompson, Vugt, Williamson, Zeleny   +30 more
core   +3 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

An investigation whether the deputy president of the African National Congress can be the successor to the president during the National Elective Conference

Africa’s Public Service Delivery & Performance Review, 2018
This is a qualitative study which investigated whether the deputy president of the African National Congress (ANC) can be the heir and elected president in the December 2017 elective conference.
Mavhungu E. Musitha, Mavhungu A. Mafukata   +1 more
doaj   +1 more source