Results 141 to 150 of about 3,322,209 (361)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

“It’s Still There, but It’s Not the Same”: Black Student Leadership in the Wake of Anti-DEI State Policy

open access: yesEducation Sciences
This study explores how Black student leaders (BSLs) at public historically white institutions (HWIs) in Florida and Georgia navigate racial battle fatigue (RBF) in the context of anti-DEI legislation.
Cameron C. Beatty   +4 more
doaj   +1 more source

Tongan women and leadership in New Zealand : a thesis presented in partial fulfilment of the requirements of the degree of Master in Business Studies at Massey University [PDF]

open access: yes, 2016
This study aims to explore how Tongan women practice leadership in New Zealand organizations. To understand the Tongan women’s leadership practice involves understanding the factors that underpin the philosophy behind their practice of leadership in ...
Paea, Seluvaia Talikivaha
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

A qualitative system review: To lead public policy advancement for workplace psychological violence injury

open access: yesSocial Sciences and Humanities Open
This article presents a qualitative system analysis informing public policy advancement for workplace psychological violence injury. It is a unique look into how a jurisdiction responds to the injury caused by workplace psychological violence (workplace ...
Wendy Bigcharles-Gaucher
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Navigating paradox in child welfare: implications for improvement science in complex human service systems

open access: yesFrontiers in Health Services
IntroductionImprovement science emphasizes the need to understand and enhance quality in complex service systems. While the field primarily has developed within healthcare, its expansion into social care requires deeper engagement with how quality is ...
Christina Evaldsson   +2 more
doaj   +1 more source

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