Results 151 to 160 of about 3,322,209 (361)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
This case study explores the challenges associated with tourism development in a village within China's Longji Rice Terrace Scenic Area. We employ Butler's (1980) Tourism Area Life Cycle model as a starting point for understanding the evolution
Courtney Kimmel +4 more
doaj
Holistic Leadership: A Model for Leader-Member Engagement and Development [PDF]
Dr. Candis Best explores the theory of holistic leadership and further provides the model and framework for it to be empirically tested. At present, Best opines that holistic leadership produces leadership which supports the development of self ...
Best, K. Candis
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Framework for Community Leadership by a Community Foundation [PDF]
In 2007 -- 2008, CFLeads convened the National Task Force on Community Leadership to define community leadership from a uniquely community foundation perspective. The result: Framework for Community Leadership by a Community Foundation.
core
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

