Risk Management and Healthcare PolicyPavani Rangachari, Alvin Tran Department of Population Health and Leadership, University of New Haven, West Haven, CT, USACorrespondence: Pavani Rangachari, Department of Population Health and Leadership, University of New Haven, 300 Boston Post Road ...
Rangachari P, Tran A
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Leadership Roles Among Physician Assistants/Associates: A 2024 National Cross-Sectional Analysis of Demographic and Occupational Characteristics. [PDF]
J Healthc LeadershBruza-Augatis M +6 more
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Clinical Learning to Leadership Development: Exploring Educational Leadership Competencies Among Undergraduate Nursing Students. [PDF]
Nurs Health SciUpendra S, Kaur J, Mathivanan JR.
europepmc +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Uncovering Pathways to Occupational Health and Safety (OHS): Presenteeism and Psychosocial Safety Climate in the JD-R-OHS Model. [PDF]
Stress HealthAkbari J, Brough P, Chan XWC.
europepmc +1 more source
Adaptive Leadership: How to Prioritize and Align Emerging Issues
, 2017 Adaptive leadership focuses on the adaptations required in response to changing environments, which essentially describes the role of the 21st Century Extension professional.
Kaufman, Eric K.
core