Results 41 to 50 of about 321,995 (264)
ABSTRACT Results of COG ANBL1221 changed treatment paradigms for patients with relapsed/refractory neuroblastoma. Chemoimmunotherapy with irinotecan/temozolomide/dinutuximab is now used as both bridge therapy following suboptimal response to induction and as treatment in first relapse.
Elizabeth Sokol +6 more
wiley +1 more source
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen +21 more
wiley +1 more source
Conceptualising Responsible Leadership in South Africa: An Interactive Qualitative Analysis
Purpose: The studying of responsible leadership as a leadership construct is facing challenges in defining, specifically within a South African context. This has been amplified by real-world challenges such as the increased unethical behaviour.
Anton Grobler, Werner Koen
doaj +1 more source
Background Gestational diabetes (GDM) and milder gestational impaired glucose tolerance (GIGT) identify women at risk of developing type 2 diabetes and cardiovascular disease later in life.
Sadia Mehmood +5 more
doaj +1 more source
The Future of Blockchain Technology and its Application and Challenges with Regard to International Migration within the African Union [PDF]
This paper explores the potential application and challenges of blockchain technology in addressing the complex issues surrounding international migration within the African Union (AU).
Charles Chatta +2 more
doaj
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia +6 more
wiley +1 more source
ABSTRACT Introduction Anthracycline‐related cardiac remodeling precedes heart failure in childhood cancer survivors. The objectives of this study were to determine the relationships between patient‐specific factors, moderate‐to‐vigorous physical activity (MVPA), and cardiac remodeling.
Hari K. Narayan +15 more
wiley +1 more source
The Use of Blockchain Technology in Identity Storage and Management [PDF]
Evolvement of Blockchain following the introduction of the internet has thrown up many issues and its application across the broad spectrum of human activities, among which is full-proof identity management system.
Gideon Simon Ghajiga +1 more
doaj
Unit Costing of Health Extension Worker Activities in Ethiopia: A Model for Managers at the District and Health Facility Level [PDF]
Background Over the last decade, Ethiopia has made impressive national improvements in health outcomes, including reductions in maternal, neonatal, infant, and child mortality attributed in large part to their Health Extension Program (HEP).
Maureen E. Canavan +4 more
doaj +1 more source
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara +7 more
wiley +1 more source

