Results 71 to 80 of about 860,270 (308)

Leadership tools for wicked problems [PDF]

, 2014
Leadership for the Greater Good is not easy to achieve. Many of the issues leaders face are so complex that they have been called ‘wicked problems’ – not in the sense of being evil, but because they seem almost intractable.
Samuel Wilson, John Fien
core  

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Unlocking Teacherpreneur Potential in Higher Education: Validating a Competency Measurement Scale

Education Sciences
This study investigated the level of teacherpreneur competency among pre-service teachers (n = 400), with an additional 400 pilot participants from the same academic context invited for exploratory factor analysis and reliability analysis.
Dihui Liu, Sukanya Chaemchoy, Pruet Siribanpitak   +2 more
doaj   +1 more source

Leadership for innovation – why manufacturing has a future in Australia [PDF]

, 2014
In this paper, business leaders discuss the leadership styles they have used to ensure their companies are manufacturing success stories, and then these experiences are analysed to outline the leadership needs for innovation in Australia.
Scott Thomson-Whiteside, Robert Wilson, Richard Simpson   +2 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Digital Pathology in South Africa: A Survey and Cross-Sectional Analysis of the Current Level of Use and Comparison With the International Community

International Journal of Telemedicine and Applications
Conclusion: The current use and adoption of digital pathology by South African histopathologists are comparable to the international community. By increasing the use of digital pathology for routine diagnostic use, we can enhance the accuracy of ...
Elsamaria Eloff, Renata Schoeman
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Evaluating action plans

South African Journal of Business Management, 1986
In 1976 Louis Gerstner wrote, 'one of the most intriguing management phenomena of the late 1960's has been the rapid spread of the corporate planning concept.
J. W. Grobbelaar, J. J. Murphy, S. R. Van Der Walt   +2 more
doaj   +1 more source