Results 31 to 40 of about 7,498 (257)

Novel Approach to Leading-Edge Vortex Suppression [PDF]

AIAA Journal, 2020
A novel approach to reduce the peak lift and pitching moment on a plunging airfoil is investigated through force, moment, and velocity measurements.
Bull, S., Chiereghin, N., Cleaver, D. J., Gursul, I.   +3 more
openaire   +1 more source

Influence of Area Distribution Along the Span Direction on Flapping Wing Aerodynamics in Hover Based on Numerical Modeling Analysis

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
This study performed a numerical investigation to explore the effect of span-wise area distribution on flapping wing aerodynamics in hovering configuration using an in-house developed flow solver.
Guilin Wu, Shuanghou Deng, Qingxi Li
doaj   +1 more source

Numerical investigation on characteristics of separation vortices between blades of two-dimensional cascade

Nihon Kikai Gakkai ronbunshu
In this study, LES calculations by OpenFOAM were performed using five blade models with different blade thicknesses (original, quarter, half, 3-quarters, and filled) to investigate the characteristics of separated and reattaching flow between blades of ...
Kosuke SETO, Koji IWANO, Yasumasa ITO, Yasuhiko SAKAI, Sho KOSAKA, Kenji YOSHIDA   +5 more
doaj   +1 more source

A species-transport model for circulation in a leading-edge vortex

Advances in Aerodynamics, 2022
In this study, we propose a model to predict circulation growth along the span of a rotating wing, in which circulation transport is represented as species transport.
Clara Giner-Morency, Jaime G. Wong
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Leading-Edge Vortex Characteristics of Surging-Translating Flexible Wings

Havacılık ve Uzay Teknolojileri Dergisi, 2023
This study experimentally investigates the flow fields around rigid and chordwise-flexible wings,performing a rectilinear translational motion starting from rest.
Mahdi Yazdanpanah, Mustafa Perçin
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Leading Edge Vortex Development on a Pitch-Up Airfoil

Volume 1B, Symposia: Fluid Machinery; Fluid Power; Fluid-Structure Interaction and Flow-Induced Noise in Industrial Applications; Flow Applications in Aerospace; Flow Manipulation and Active Control: Theory, Experiments and Implementation; Fundamental Issues and Perspectives in Fluid Mechanics, 2013
The dynamics of leading edge vortex (LEV) on an airfoil due to pitch-up motion is investigated using computational fluid dynamics techniques to solve the Navier-Stokes equations on composite overlapping grids. The objectives are to (1) quantify the contribution of circulatory effects caused by vortex development, and non-circulatory effects due to ...
Kyle Hord, Yongsheng Lian
openaire   +1 more source