Results 41 to 50 of about 3,507,797 (292)
Novel Approach to Leading-Edge Vortex Suppression [PDF]
AIAA Journal, 2020 A novel approach to reduce the peak lift and pitching moment on a plunging airfoil is investigated through force, moment, and velocity measurements.
Bull, S. +3 more
openaire +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
On the effects of leading edge vortex generators on an OA209 airfoil [PDF]
, 2009 Leading edge vortex generators have been found to significantly increase the aerodynamic performance of an airfoil under dynamic stall conditions. However, the principle of operation of these devices is still unclear.
Gardner, Anthony +3 more
core
Leading-Edge Vortex Characteristics of Surging-Translating Flexible Wings
Havacılık ve Uzay Teknolojileri Dergisi, 2023 This study experimentally investigates the flow fields around rigid and chordwise-flexible wings,performing a rectilinear translational motion starting from rest.
Mahdi Yazdanpanah, Mustafa Perçin
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Advances in Mechanical Engineering, 2014 This paper presents wind tunnel experiment on two delta wing configurations which are differentiated by their leading edge profiles: sharp and round-edged wings. The experiments were performed as a part of the delta wing aerodynamics research development
Shabudin Mat +7 more
doaj +1 more source
Continuous Reynolds number effect analysis of the influence of vortex generator on the aerodynamic performance of airfoil [PDF]
Journal of Hebei University of Science and TechnologyIn order to effectively improve the power generation efficiency of large wind turbines, studies on the optimization measures for the aerodynamic performance of wind turbine airfoils were conducted. Wind tunnel experiments were conducted to systematically
Yaya JIA +4 more
doaj +1 more source