Results 31 to 40 of about 212,768 (263)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Dyna, 2018 This paper presents a useful model to determine the washing periods and to indicate the pollution levels of electrical insulators. The behavior of leakage current, which is one indicator of the presence of pollutants on the insulator surfaces, was ...
Rafael Castillo-Sierra +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Analysis and modeling of leakage current sensor under pulsating direct current
AIP Advances, 2017 In this paper, the transformation characteristics of current sensor under pulsating DC leakage current is investigated. The mathematical model of current sensor is proposed to accurately describe the secondary side current and excitation current.
Kui Li +5 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Iranian Journal of Electrical and Electronic Engineering, 2014 Metal oxide surge arresters (ZNO) are used widely in power system to protect equipments from over voltages. Non uniform potential distribution leads to the depressed service life and low safe reliability, so grading ring is applied on HV surge arrester ...
M. Khodsuz, M. Mirzaie
doaj
Energies, 2020 Recently, eco-friendly energy conversion policies have been being promoted through de-nuclearization and de-coal. For this purpose, a super grid should be built to optimize sustainable renewable energy resources such as solar and wind power. Accordingly,
Heon-Gyeong Lee, Jin-Gyu Kim
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Crystals, 2021 AlGaN/GaN Schottky barrier diodes (SBDs) with high Al composition and high temperature atomic layer deposition (ALD) Al2O3 layers were investigated.
Jae-Hoon Lee, Jung-Hee Lee, Ki-Sik Im
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