Results 51 to 60 of about 474,823 (307)

Influence of Internal Flow on the Performance of High-Speed Centrifugal Pumps with a Fully Sealed Structure

open access: yesApplied Sciences, 2022
A high-speed centrifugal pump with a fully sealed structure has the advantages of a small size, no external leakage, and being pollution-free. The inner leakage passage of a pump with a fully sealed structure includes the tip clearance and the hub ...
Xinyi Lin   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Quantifying Information Leaks Using Reliability Analysis [PDF]

open access: yes, 2014
acmid: 2632367 keywords: Model Counting, Quantitative Information Flow, Reliability Analysis, Symbolic Execution location: San Jose, CA, USA numpages: 4acmid: 2632367 keywords: Model Counting, Quantitative Information Flow, Reliability Analysis, Symbolic
d Amorim, M   +4 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Optimization Design and Analysis of Supersonic Tandem Rotor Blades

open access: yesEnergies, 2020
To explore the flow mechanism and improve the performance of supersonic tandem rotor blades, the supersonic rotor Rotor37 is taken as the prototype and redesigned to an original supersonic tandem rotor.
Ruochi Pan, Zhaoyun Song, Bo Liu
doaj   +1 more source

Universal Programmable Portable Measurement Device for Diagnostics and Monitoring of Industrial Fluid Power Systems

open access: yesSensors, 2021
This paper presents a new universal programmable portable measuring device (PMD) as a complete, accurate, and efficient solution for monitoring and technical diagnostics of industrial fluid power systems.
Ryszard Dindorf, Piotr Wos
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Vibrations in Leaking Spherical Valves with Annular Seal

open access: yesProceedings, 2018
Hydroelectric power plants are used worldwide to cover varying electricity demands. The Salime hydroelectric power plant, which is located at Asturias, Spain, has four hydro turbines with a total design capacity of 128 MW.
Hesham Awad   +2 more
doaj   +1 more source

Acoustic leak detection technology for multiphase flow pipeline

open access: yesYou-qi chuyun, 2020
At present, the multiphase flow technology is applied increasingly in oil and gas mixed transportation system.However, the safety problems of multiphase pipeline are much more complicated than that of single-phase pipeline. Acousticsensing technology has
Jian JI   +4 more
doaj   +1 more source

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