Gut Microbiota, Leaky Gut, and Autoimmune Diseases [PDF]
Frontiers in Immunology, 2022 With the rising prevalence of autoimmune diseases, the role of the environment, specifically the gut microbiota, in disease development has grown to be a major area of study.
Xin M Luo
exaly +8 more sources
Microorganisms, 2018 ‘Leaky gut’ syndrome, long-associated with celiac disease, has attracted much attention in recent years and for decades, was widely known in complementary/alternative medicine circles.
Mark E Obrenovich
exaly +6 more sources
Leaky Gut As a Danger Signal for Autoimmune Diseases [PDF]
Frontiers in Immunology, 2017 The intestinal epithelial lining, together with factors secreted from it, forms a barrier that separates the host from the environment. In pathologic conditions, the permeability of the epithelial lining may be compromised allowing the passage of toxins,
Xin M Luo, Chris Reilly, Qinghui Mu
exaly +7 more sources
Leaky Gut and the Ingredients That Help Treat It: A Review [PDF]
Molecules, 2023 The human body is in daily contact with potentially toxic and infectious substances in the gastrointestinal tract (GIT). The GIT has the most significant load of antigens. The GIT can protect the intestinal integrity by allowing the passage of beneficial
Marvin Moncada
exaly +6 more sources
Severity of atopic dermatitis is associated with gut-derived metabolites and leaky gut-related biomarkers [PDF]
Scientific ReportsDysbiosis of the gut microbiota may contribute to metabolic dysregulation, intestinal barrier disruption, and inflammatory disorders. The objective was to identify gut-derived metabolites and leaky gut biomarkers linked to atopic dermatitis.
Leszek Blicharz +17 more
doaj +3 more sources
Metabolites, 2021 A leaky gut can trigger chronic inflammation and poses a primary risk for metabolic diseases. This study established a relationship between intestinal integrity (leaky gut) and metabolic health in a general population.
Edith Feskens +2 more
exaly +3 more sources
Is There an Exercise-Intensity Threshold Capable of Avoiding the Leaky Gut?
Frontiers in Nutrition, 2021 Endurance-sport athletes have a high incidence of gastrointestinal disorders, compromising performance and impacting overall health status. An increase in several proinflammatory cytokines and proteins (LPS, I-FABP, IL-6, IL-1β, TNF-α, IFN-γ, C-reactive ...
Octavio Franco, Pétriz B
exaly +3 more sources
Lactiplantibacillus plantarum 22 A-3 ameliorates leaky gut in mice through its anti-inflammatory effects [PDF]
Scientific ReportsThere are limited studies on the improvement of leaky gut with minor inflammation associated with various diseases. To explore the therapeutic potential of Lactiplantibacillus plantarum 22 A-3, a member of the Lactobacillus species, in addressing a leaky
Takashi Kobayashi +9 more
doaj +2 more sources
Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut [PDF]
Cells, 2023 The intestinal barrier is the main contributor to gut homeostasis. Perturbations of the intestinal epithelium or supporting factors can lead to the development of intestinal hyperpermeability, termed “leaky gut”.
Michele d’Angelo +13 more
doaj +2 more sources
Effects of Limosilactobacillus reuteri strains PTA-126787 and PTA-126788 on intestinal barrier integrity and immune homeostasis in an alcohol-induced leaky gut model [PDF]
Scientific ReportsIntestinal barrier is a first line of defense that prevents entry of various harmful substances from the lumen into the systemic environment. Impaired barrier function with consequent translocation of harmful substances into systemic circulation (“leaky ...
Dharanesh Gangaiah +11 more
doaj +2 more sources