A review of the pathogenesis of epilepsy based on the microbiota-gut-brain-axis theory
The pathogenesis of epilepsy is related to the microbiota-gut-brain axis, but the mechanism has not been clarified. The microbiota-gut-brain axis is divided into the microbiota-gut-brain axis (upward pathways) and the brain-gut-microbiota axis (downward ...
Wentao Yang +5 more
doaj +1 more source
Laminaria japonica Extract Enhances Intestinal Barrier Function by Altering Inflammatory Response and Tight Junction-Related Protein in Lipopolysaccharide-Stimulated Caco-2 Cells. [PDF]
In the normal physiological state, intestinal epithelial cells act as a defensive frontline of host mucosal immunity to tolerate constant exposure to external stimuli.
Ding +13 more
core +1 more source
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai +6 more
wiley +1 more source
Fibromyalgia: A Unifying Neuroendocrinologic Model for Understanding Its Pathophysiology [PDF]
Fibromyalgia is believed to affect at least 2% of the population. Despite advances in the scientific understanding of the derangements of central and peripheral pain processing mechanisms in fibromyalgia, no current models of its pathophysiology account ...
Peter Dorsher
core +1 more source
Utility of serological markers in inflammatory bowel diseases: Gadget or magic? [PDF]
The panel of serologic markers for inflammatory bowel diseases (IBD) is rapidly expanding. Although anti-Saccharomyces cerevisiae antibodies (ASCA) and atypical perinuclear antineutrophil cytoplasmic antibodies (P-ANCA) remain the most widely ...
Altorjay, István +3 more
core +1 more source
Smart Catheters for Diagnosis, Monitoring, and Therapy
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman +12 more
wiley +1 more source
The heart and the gut seem to be two organs that do not have much in common. However, there is an obvious and clinically relevant impact of gut functions on the absorption of drugs and oral therapies on the one hand. On the other hand, the gut determines
Rogler, Gerhard, Rosano, Giuseppe
core
Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence +2 more
core +2 more sources
Leaky gut biomarkers in depression and suicidal behavior [PDF]
ObjectiveInflammation is associated with major depressive disorder (MDD) and suicidal behavior. According to the ‘leaky gut hypothesis’, increased intestinal permeability may contribute to this relationship via bacterial translocation across enterocytes.
L. Ohlsson +7 more
openaire +4 more sources
3D‐Printed Gastrointestinal Stents: In Vivo Evaluation in a Swine Small Bowel Perforation Model
Gastrointestinal fistulae and perforations can lead to severe complications including sepsis and patient death. In this work, the efficacy of 3D‐printed gastrointestinal stents composed of poly‐lactic‐acid (PLA) was evaluated in an in vivo swine model.
Gweniviere Capron +9 more
wiley +1 more source

