Results 31 to 40 of about 325,268 (268)

Enabling lean design management: An LOD based framework [PDF]

open access: yes, 2016
Question: How can we use the Level of Development (LOD) concept to better develop BIM models under a Transformation, Flow and Value (TFV) perspective?
Hamzeh, Farook R.   +1 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Bibliometric survey on Lean Healthcare in Project Management [PDF]

open access: yes, 2022
The hospital environment is very conducive to incorporate the Lean philosophy, as this organizations must provide quality services with a comprehensive resource restriction.
Huamanchumo Gutierrez, Ruben   +2 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Lean tools applied in urban public transportation [PDF]

open access: yes, 2019
The present paper has the objective of proposing an application of the tools of the lean philosophy in urban public transport companies of the north of Santa Catarina.
Garcia, Janaina Renata   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Consequências da implantação pontual de ferramentas Lean [PDF]

open access: yes, 2016
A manufatura lean vem sendo amplamente discutida e difundida desde os primórdios de sua criação. Entretanto, este enfoque produz alguns efeitos contrários, como o problema das empresas que não adotam a filosofia como um todo utilizando apenas algumas ...
Ferreira, Caio Cesar   +4 more
core  

Lean and the circular economy: A systematic literature review

open access: yes, 2022
Lean is a well-renowned strategy for increasing the value of products by minimizing waste. The circular economy is a new paradigm designed to mitigate environmental problems in production activities.
Salibi, José Geraldo de Oliveira Rangel   +3 more
core  

The precast construction industry and lean construction tools: flow-based management strategy [PDF]

open access: yes, 2022
: The Toyota Production System (TPS) formulated the referential base for the elaboration of lean construction principles, called Lean Construction and organized by Lauri Koskela, in 1992.
Riffel, Elias
core  

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