Results 81 to 90 of about 1,091,104 (305)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Production and Manufacturing Research: An Open Access Journal, 2019 Introduction: Lean is increasingly used by garment manufacturers to increase productivity for reducing costs and lead time. Yet, it has not been documented in a review whether lean actually improves productivity, and it is an open question whether lean ...
Abu Hamja, Malek Maalouf, Peter Hasle
doaj +1 more source
Construction Innovation: The Implementation of Lean Construction towards Sustainable Innovation [PDF]
, 2011 The prevalent theory of construction has been seen as a hindrance to construction innovation. The concept of lean construction is concerned with the application of lean thinking to the construction industry.
Goulding, Jack Steven +2 more
core
Improving access to health services – Challenges in Lean application [PDF]
, 2015 Purpose: Healthcare organisations face significant productivity pressures and are undergoing major service transformation. This paper serves to disseminate findings from a Lean healthcare project using a NHS Single Point of Access environment as the ...
Bamford, David +3 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
, 2013 This book gives an account on the progress of C. Rolim Engenharia regarding lean and green targets in recent years. It contains a theoretical introduction, a history of lean and green developments in the company, research papers
Koskela, Lauri
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Automation, Lean, Six Sigma: Synergies for improving laboratory efficiency [PDF]
Journal of Medical Biochemistry, 2010 The Pathology Services worldwide, surrounded by products are today requesting solutions. The approach aims towards the brain-to-brain cycle between caregivers and laboratory professionals.
Villa Davide
doaj
Delivering and sustaining change through implementation of a lean management system : a journey towards health improvement : a thesis presented in partial fulfilment of the requirements for the degree of Master of Business Studies in Management at Massey University, Albany, New Zealand [PDF]
, 2017 In this ever-changing world organisations seek to be adaptive and innovative and in response they are adopting new ways of working. Approaches to managing change have been well documented and have progressed as a deeper understanding of change and the ...
Winstone, Tim
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source