Results 71 to 80 of about 3,203,695 (300)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

APPLICATION OF BIM DURING LEAN CONSTRUCTION OF HIGH-RISE BUILDINGS

Civil Engineering Journal, 2019
At present, the constructionindustry is in urgent need of a big transformation from the traditional extensive development model to achieve transformation and upgrading.
Suchun Yang
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Investigating the impact of lean construction principles on contractors’ project performance in Ethiopia using PLS-SEM [PDF]

Journal of Project Management
The construction industry faces challenges, such as schedule overruns, cost overruns, poor quality, and safety issues. Lean construction is a valuable concept for waste reduction and improving project performance.
Achamyelew Maru, Wubshet Jekale , Belachew Asteray   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Examining the interaction between lean and sustainability principles in the management process of AEC industry

Ain Shams Engineering Journal, 2018
Architecture, Engineering and Construction (AEC) industry is classified as a huge consumer of natural resources. It consumes 50% of natural material resources, 40% of energy and is responsible for 50% of total waste.
Laila M. Khodeir, Reem Othman
doaj   +1 more source

Cause Analysis of Hindering On-Site Lean Construction for Prefabricated Buildings and Corresponding Organizational Capability Evaluation

Advances in Civil Engineering, 2020
As prefabricated buildings play a significant role in the global fight against the new coronavirus “COVID-19,” they attract more global attention than other types of buildings.
Zhenmin Yuan, Ziyao Zhang, Guodong Ni, Chen Chen, Wenshun Wang, Jingke Hong   +5 more
doaj   +1 more source

Lean construction as a panacea for poor construction projects performance

ITEGAM-JETIA, 2020
Recurring problems in the delivery of construction projects have been time and cost overruns, poor quality, poor health and safety, waste and loss of value.
William Nkeonyeasua Nwaki, Chidiebere Emmanuel Eze   +1 more
doaj   +1 more source

Editorial : Lean Construction

Building & Management, 2018
Editorial : Lean ...
Piña Ramírez, Carolina, Martínez Pérez, Inmaculada, González Rodrigo, Sonsoles   +2 more
openaire   +4 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source