Results 91 to 100 of about 319,318 (302)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Incorporating Lean Construction agent into the Building Standards Act: the Spanish case study
Organization, Technology and Management in Construction: An International Journal, 2017 There is a demand for lean construction in Europe; even though lean construction is still an emerging field and there is growing interest, there are no regulations on this topic.
Brioso Xavier, Humero Antonio
doaj +1 more source
Advancing lean implementation within a construction supply chain [PDF]
, 2018 This investigation leads to critical recommendations for advancing the Small and Medium Enterprises (SMEs) for lean implementation within a Construction Supply Chain (CSC).
Arif, Mohammed, Saini, Mandeep
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
LEAN PROCUREMENT: THE USE OF LEAN CONSTRUCTION TECHNIQUES IN PROJECT VALUE ENHANCEMENT [PDF]
, 2012 Lean construction is characterised by a set of clear objectives in project delivery involving the concurrent design of products and processes, and the application of production control throughout the project life cycle to maximise value for money to ...
Goulding, Jack Steven +2 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Analysis Framework for the Interaction Between Lean Construction and Building Information Modelling [PDF]
Building with Building Information Modelling (BIM) changes design and production processes. But can BIM be used to support process changes designed according to lean production and lean construction principles? To begin to answer this question we provide
Dave, Bhargav +3 more
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An experience of introducing last planner into a UK construction project [PDF]
, 2003 The Last Planner methodology developed by the Lean Construction Institute is a production control tool which has possible benefits for improving planning in the UK construction industry. Its application has been considered in countries outside the UK but
Johansen, Eric, Porter, Geoff
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source