Results 111 to 120 of about 319,318 (302)
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
A hybrid approach using entropy and TOPSIS to select key drivers for a successful and sustainable lean construction implementation. [PDF]
Dehdasht G +3 more
europepmc +1 more source
Is good enough 'making do'?: An investigation of inappropriate processing in a small design and build company [PDF]
Purpose: The aim was to address behaviour that led to inappropriate processing in a small design and build contracting organisation that employs direct labour. The objective was to reduce process waste and improve the value delivered to clients.
Emmitt, S, Mertia, B, Pasquire, C
core
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Reforming Project Management: The Role of Lean Construction [PDF]
Project management as taught by professional societies and applied in current practice must be reformed because it is inadequate today and its performance will continue to decline as projects become more uncertain, complex and pressed for speed.
Howell, Gregory A., Koskela, Lauri
core
The Lean Cuisine+ notation revised [PDF]
The Lean Cuisine+ notation was developed by Chris Phillips (1995) as an executable semi-formal graphical notation for describing the underlying behaviour of event-based direct manipulation interfaces.
Scogings, Chris
core
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
The construction sector is a fundamental pillar of the economy and should consequently lead in implementing effective management systems. Lean Construction (LC) philosophy sees production as a transformation, flow, and value process.
Gonzalo Garcés +4 more
doaj +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source

