Results 121 to 130 of about 319,318 (302)
Towards a lean model for production management of refurbishment projects, VTT Technology: 94 [PDF]
This is the Stage 3 Report for the ApRemodel project, which aims at improving processes for multi-occupancy retrofit by generating a lean model for project delivery.
Kemmer, S, Koskela, LJ, Nykänen, V
core
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Modular assembly with postponement to improve health, safety & productivity in construction [PDF]
This paper presents the outcome of an engineering study as part of the design and development of a lean and agile construction system and in particular its supply chain component.
Bower, D +3 more
core
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Lean Framework for Minimizing Construction and Demolition Waste in Zimbabwe
Construction and demolition waste (CDW) constitute a menace in Zimbabwe. The industry’s image is tainted by rampant disposal on roadsides, in watercourses, and in landfills. Concerted practical efforts to proffer solutions to the problems of CDW disposal
Kurauwone Maponga +2 more
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The magic of the Last Planner® System for Nigerian construction [PDF]
Extremely poor economic performance of the Nigerian construction industry suggests that non-value adding activities are prevalent, which result not only in the reduction of contractors’ profit margin but economic loss for the country in general.
Ameh, OJ, Daniel, EI, Pasquire, C
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Holistic Learning: A workforce development paradigm [PDF]
The development of workforce knowledge, skills and attitudes are widely acknowledged in extant literature as being pivotal levers to deliver process improvement and efficiency.
Adjaie John, Godfaurd +3 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source

