Results 81 to 90 of about 319,318 (302)
Implementing lean: UK culture and systems change [PDF]
, 2004 For the IGLC 12 Conference the authors reported the results of implementing Last PlannerTM methods with a large UK contracting company. The projects studied demonstrated some success but also some cultural, organizational and systemic barriers to its ...
Greenwood, David +2 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
CONCEPTUAL TRANSFORMATION PROCESS MODEL FOR SUSTAINABILITY IN THE INFRASTRUCTURE SECTOR
Journal of Construction Project Management and Innovation, 2016 Business as usual (BAU) model of infrastructure delivery is contrary to the needs of sustainability in the built environment. This difference necessitates a South African study that is focus on sustainability in the infrastructure sector.
Rasheed Babatunde ISA +2 more
doaj +1 more source
Creating Social Value within the Delivery of Construction Projects [PDF]
, 2018 The purpose of this paper is to present the current knowledge surrounding social value and show how lean approach supports social value realisation in the delivery of construction projects. A critical literature review was adopted, to gather the current
Daniel, Emmanuel, Pasquire, Christine
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
PUBLIC PRIVATE PARTNERSHIP FOR LEAN SUSTAINABLE DEVELOPMENT IN CONSTRUCTION
Journal of Construction Project Management and Innovation, 2012 Sustainability of construction projects has become a major issue facing decision-makers, developers, city and urban planners as well as designers worldwide.
Ayman Othman +1 more
doaj +1 more source
Hard, soft or lean? Planning on medium size construction projects [PDF]
, 1999 In a paper presented to the 11th Annual ARCOM Conference, Johansen examined the way that managers and planners in medium sized construction projects plan in a flexible manner.
Greenwood, David, Johansen, Eric
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Application of Lean Concepts in Building Construction [PDF]
, 2017 The construction industry has demonstrated a decline in productivity when compared to other industries over the past twenty years. In order to overcome this defect in the construction industry, the lean concept has been introduced.
M, S. P. (Sumayya)
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