Results 111 to 120 of about 221,276 (349)

Penerapan Lean Manufacturing pada Industri Proses dengan Fokus pada Pengolahan Tepung Ikan [PDF]

open access: yes, 2016
Opportunities of local fishmeal raw material derived from fish waste is enormous. Besides will not reduce the quality of fish meal, fish waste utilization will reduce the impact of fish waste which is currently not managed properly. In CV Pendawa Kencana
Hermawan, A. T. (Andy)   +1 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Manufacturing technology adoption among lean manufacturers: An initial study [PDF]

open access: yes, 2012
Lean manufacturing is a technique that allows work to be performed without bottlenecks or delays while eliminating wasteful activities by linking and balancing equal amounts of work steps together, enabling products to be consumed directly into the next ...
Mohamed Ismail, Risyawati, Wee, H. S
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Sustainable manufacturing: Exploring antecedents and influence of Total Productive Maintenance and lean manufacturing

open access: yesAdvances in Mechanical Engineering, 2019
This article explores the environment-related antecedents and the influence of Total Productive Maintenance and other lean manufacturing practices on environmental sustainability.
Ping-Kuo Chen   +3 more
doaj   +1 more source

PENERAPAN LEAN MANUFACTURING UNTUK MEREDUKSI WASTE DI INDUSTRI SKALA UKM

open access: yesJ@ti Undip: Jurnal Teknik Industri, 2012
Lean Manufacturing merupakan konsep manufaktur untuk menghasilkan produk yang efisien dengan mengurangi biaya produksi melalui efisiensi. Dalam konsep Lean, dikenal 7 macam pemborosan yang meliputi produksi berlebih, transportasi material yang berlebihan,
Darminto Pujotomo, Raditya Armanda
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

How Blockchains Improve Lean Manufacturing Tools in the Industry 4.0 Context

open access: yesEngineering Proceedings
Lean manufacturing (LM) is one of the strongest tools used by manufacturing companies to improve and optimize their processes, making them more performant and agile.
Rouidi Ibrahim   +2 more
doaj   +1 more source

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