Results 91 to 100 of about 214,336 (304)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Digital Leadership and Lean Manufacturing: An Analysis Using an Importance–Performance Map
Forum Scientiae OeconomiaThe success of lean manufacturing practices in Industry 4.0 is highly dependent on people and technology; therefore, an appropriate leadership style is essential when pursuing the implementation of lean manufacturing.
Maria Marisela Vargas-Salgado +4 more
doaj +1 more source
Relationship between lean manufacturing tools and their sustainable economic benefits. [PDF]
Int J Adv Manuf Technol, 2022 Díaz-Reza JR +4 more
europepmc +1 more source
MODELING AND SIMULATION OF A LEAN SYSTEM. CASE STUDY OF A PAINT LINE IN A FURNITURE COMPANY [PDF]
Since they were first developed, lean methodologies have grown in importance and scope and have been applied in both manufacturing and service. However, determining how to transform a common manufacturing company into a lean one, as well as how to ...
Ki-Chan NAM +2 more
core
A case study of lean, sustainable manufacturing [PDF]
, 2010 A small furniture production company has integrated lean tools and sustainability concepts with discrete event simulation modeling and analysis as well as mathematical optimization to make a positive impact on the environment, society and its own ...
Miller, Geoff +2 more
core +3 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Effect of lean manufacturing tools on sustainability: the case of Mexican maquiladoras. [PDF]
Environ Sci Pollut Res Int, 2022 García-Alcaraz JL +5 more
europepmc +1 more source
The Integration of a Lean Manufacturing Competency-based Training Course into University Curriculum [PDF]
, 2010 The manufacturing industry has become extremely competitive in nature and each company’s survival depends on gaining an edge in their respective field. Lean manufacturing has emerged as the leading management philosophy in this struggle.
Cooper, John J., Jr.
core +1 more source
Set-Based Concurrent Engineering process within the LeanPPD environment [PDF]
, 2011 This paper presents a newly defined set-based concurrent engineering process, which the authors believe addresses some of the key challenges faced by engineering enterprises in the 21st century. The main principles of Set-Based Concurrent Engineering (
Al-Ashaab, Ahmed +5 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source