Results 131 to 140 of about 221,276 (349)

Penerapan Lean Manufacturing Untuk Mereduksi Waste Di Industri Skala UKM [PDF]

open access: yes, 2011
Lean Manufacturing merupakan konsep manufaktur untuk menghasilkan produk yang efisien dengan mengurangi biaya produksi melalui efisiensi. Dalam konsep Lean, dikenal 7 macam pemborosan yang meliputi produksi berlebih, transportasi material yang berlebihan,
Armanda, R. (Raditya)   +1 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Inclusive tool to assess lean manufacturing maturity and its relationship with the size or location of the company in Greater Montreal, Canada

open access: yesCogent Engineering
Manufacturing companies operate in aggressive environments and require high productivity for survival. This study examined the implementation status of lean manufacturing practices in a sample of Greater Montreal’s industries by assessing maturity levels
Didérot Déraillet Tadja   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Lean manufacturing implementation in food and beverage SMEs in Tanzania: using structural equation modelling (SEM)

open access: yesManagement System Engineering
Currently globally industries are increasingly adopting lean production methods to enhance operational efficiency and overall business performance. Lean tools, which significantly reduce waste, are particularly beneficial for small and medium enterprises
Juma M. Matindana, Mary J. Shoshiwa
doaj   +1 more source

An accounting system to support process improvements: transition to lean accounting [PDF]

open access: yes, 2010
From the last two decades of the 20th Century on, many companies have adopted production strategies that could be termed “lean manufacturing”. Lean team leaders state that traditional costing systems fail to properly assess their operational improvements
Fortuny Santos, Jordi   +1 more
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

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