Results 41 to 50 of about 1,391,913 (277)
International Journal of Sustainable Engineering, 2017 The modern manufacturing organisations have been adopting both lean and sustainable manufacturing paradigms to survive in the competitive environment. Lean and sustainable strategies aim at achieving productivity improvement by streamlined processes and ...
R. Ben Ruben, P. Asokan, S. Vinodh
doaj +1 more source
Jurnal Aplikasi Bisnis dan Manajemen, 2019 The purposes of this research were to identify factors affecting the success and failure in implementing the continuous lean manufacturing (LM) of woodworking industry in Indonesia.
Aminudin Soetara +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Lean Manufacturing: implantación 5S [PDF]
3C Tecnología_Glosas de innnovación aplicadas a la pyme, 2016 [EN] The implementation of the 5S tool across SME’s, aims to eliminate waste and seek an environment of clean and tidy. This is essential to follow the five key steps with the support of available resources and adapt to the culture of the company.
Manzano Ramírez, María +1 more
openaire +2 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Cost-reduction of waste processing through manufacturing knowledge [PDF]
, 2006 The rapid transformation of the Waste Management sector has significantly altered the nature of the traditional waste processing business and the nature of competencies required to manage it.
Beautru-Frain, Valerie
core +4 more sources
Lean manufacturing, leadership and employees: the case of UAE SME manufacturing companies
Production and Manufacturing Research: An Open Access Journal, 2020 Successful lean implementation to SMEs poses great challenges. Although lean principles, tools and strategies for implementation are widely known and well documented, companies still struggle.
Mudhafar Alefari +2 more
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source