Results 61 to 70 of about 30,769 (308)
The contribution of lean thinking to the maintenance of manufacturing systems [PDF]
, 2003 Despite many significant contributions and advances of lean thinking recorded in articles, books, and industrial case studies, its impact upon the maintenance function has not been fully investigated.
Davies, Christopher
core
From Micro to Macro: A Comprehensive Study of Lean Manufacturing Tools in Tanzanian Industries
Engineering ReportsThe study aimed to establish the adoption status of tools and practices, drivers, and barriers for Lean Manufacturing (LM) for the Tanzanian context based on the industry size. The study adopted a survey research design.
Francis D. Sinkamba +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Cost-reduction of waste processing through manufacturing knowledge [PDF]
, 2006 The rapid transformation of the Waste Management sector has significantly altered the nature of the traditional waste processing business and the nature of competencies required to manage it.
Beautru-Frain, Valerie
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Identifying Real Cost Saving in Lean Manufacturing
, 2013 Lean manufacturing is well-known as an effective means toward cost savings, but to convince management to support a culture shift to implement a lean manufacturing program there must be confidence in understanding what real effective and measurable lean ...
Jones, Bryan
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Exploring lean manufacturing practices' influence on process innovation performance
, 2018 Little is known about the effects of lean manufacturing practices on the process innovation performance of manufacturing organisations. This research aims to fill this gap and explore the aforementioned interdependency. A research framework consisting of
Vikas Kumar +6 more
core +1 more source
Coexistence of the BRC Standard for Packaging and the Lean Manufacturing methodology
Engineering Management in Production and Services, 2018 This study aimed to explore the potential impact of the Lean Manufacturing methodology on the implementation and functioning of the BRC Standard for Packaging.
Urban Wiesław +3 more
doaj +1 more source