Results 51 to 60 of about 30,769 (308)
Exploration of the integration of Lean and environmental improvement [PDF]
, 2009 With increasing awareness of the environmental damage that is occurring as a result of human activities, there are also increasing pressures on manufacturing companies to reduce environmental impacts.
Biggs, Claire
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Analysing the adoption of Lean production in remanufacturing industry
Journal of Industrial Engineering and Management, 2018 Purpose: This paper aims to analyse the challenges of lean manufacturing implementation in the remanufacturing industry. The research was undertaken in three types of remanufacturing company, torque converter, gearbox, and jet engine remanufacturers ...
Anjar Priyono, Fazli Idris
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The contribution of industry 4.0 to lean manufacturing
, 2023 The term Industry 4.0 (I.4.0) has often been cited and is directly linked to the future of manufacturing activities, and within this context, interfaces with other concepts such as Lean Manufacturing occur, and the latter can benefit from the benefits ...
Oian, Carlos Alberto
core
Lean Office in a Manufacturing Company
, 2021 Since its inception with Toyota, the lean approach has been a growing point of interest in various industries and organizations worldwide. However, the focus of attention, in terms of its application in the literature, has remained constant in improving the performance of production processes compared to improving that of offices.
Costa F., Kassem B., Staudacher alberto
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A customised lean model for a Chinese aerospace OEM (Original Equipment Manufacturer) [PDF]
, 2011 The aim of this research is to introduce Lean Thinking in a systematic and cost effective way; moreover, it is to bring Lean Principles and apply Lean Tools to the new aerospace companies.
Li, Chao
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source