The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Influence of different sports on fat mass and lean mass in growing girls
Journal of Sport and Health Science, 2017 Purpose: The aim of this study was to analyze and compare the effects of different sports (swimming, football, basketball, and handball) on fat mass and lean mass in prepubertal and pubertal girls. Methods: Two hundred girls (10.6 ± 1.5 years old, Tanner
Esther Ubago-Guisado +5 more
doaj +1 more source
Intrarectal administration of hCG (Human Choriogonadotropin) and fat loss as assessed by Dual energy X-ray absorptiometry (DXA) in experimental animals. [PDF]
, 2012 Our studies suggest that in experimental animals, submitted to a hypocaloric diet, the intrarectal administration of hCG (Human Chorionic Gonadotropin) decreases body fat and increases lean mass content in relative values to a greater extent that control
Alejandro Kaniuk +4 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Older postmenopausal women with lower lean mass have hypermethylated sites in the PI3K-Akt pathway
Frontiers in Physiology, 2023 Introduction: The decrease in lean mass is directly related to the loss of independence, muscle strength, and worse quality of life over the years.
Igor Massari Correia +9 more
doaj +1 more source
Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients.
Medicine & Science in Sports & Exercise, 2019 AIM To examine changes in lean mass during hospitalization in geriatric patients and the effect of muscle activation by neuromuscular electrical stimulation.
A. Karlsen +8 more
semanticscholar +1 more source
Multi-mass solvers for lattice QCD on GPUs
, 2011 Graphical Processing Units (GPUs) are more and more frequently used for lattice QCD calculations. Lattice studies often require computing the quark propagators for several masses.
A. Alexandru +19 more
core +1 more source
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus [PDF]
, 2017 Bone mineral density is known to be a heritable, polygenic trait whereas genetic variants contributing to lean mass variation remain largely unknown. We estimated the shared SNP heritability and performed a bivariate GWAS meta-analysis of total-body lean
Ackert-Bicknell, C. (Cheryl) +33 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The potential therapeutic effects of creatine supplementation on body composition and muscle function in cancer [PDF]
, 2018 Low muscle mass in individuals with cancer has a profound impact on quality of life and independence and is associated with greater treatment toxicity and poorer prognosis.
Fairman, C M +5 more
core +2 more sources