Results 31 to 40 of about 98,677 (296)

A new Lean Six Sigma framework for improving competitiveness

open access: yesActa Scientiarum: Technology, 2019
Manufacturing companies strive for ever-increasing competitiveness through productivity and quality. This goal can be achieved through the implementation of lean manufacturing and six sigma methodologies.
Iris Bento da Silva   +3 more
doaj   +1 more source

The Key Success Factors for Lean Manufacturing versus Six Sigma [PDF]

open access: yes, 2016
The aim of this study is to investigate and identify the key success factors of implementing lean manufacturing and six sigma in separate ways. The study applies a quantitative approach and statistical analysis to determine the results collected from the
A. Kobi, C. Robledo, I. Alhuraish
core   +3 more sources

Lean Six Sigma: A new approach to the management of patients undergoing prosthetic hip replacement surgery [PDF]

open access: yes, 2015
Rationale, aims and objectives In 2012, health care spending in Italy reached €114.5 billion, accounting for 7.2% of the Gross Domestic Product (GDP) and 14.2% of total public spending.
Alessandro Russo, Mario   +8 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

IMPLEMENTASI KONSEP LEAN MANUFACTURING GUNA MENGURANGI PEMBOROSAN DI LANTAI PRODUKSI

open access: yesOPSI, 2018
CV Marga Jaya (Pabrik II) adalah perusahaan yang bergerak di bidang pembuatan paving/conblock secara masal. CV Marga Jaya (Pabrik II) selalu berusaha mengurangi pemborosan yang terjadi selama proses produksi paving/conblock.
Almer Panji Pradana   +2 more
doaj   +1 more source

Penerapan Metode Lean Six Sigma Dalam Upaya Rekrutmen Peserta PPU Badan Usaha: Study Kasus Proses Telemarketing Kantor Cabang Jakarta Selatan

open access: yesJurnal Jaminan Kesehatan Nasional, 2021
Pandemi covid-19 selama tahun 2020 membuat capaian peserta khusus segmen Pekerja Penerima Upah (PPU) mengalami penurunan, khususnya di kantor cabang Jakarta Selatan.Penelitian ini bertujuan untuk mengetahui dampak penerapan metode Lean Six Sigma dalam ...
Teguh Wijaya   +3 more
doaj   +1 more source

Lean Six Sigma Leadership in Health Care Organizations [PDF]

open access: yes, 2017
The reason for choosing this topic was the want to change the current employee settings in health care organizations. Using Lean Six Sigma Leadership has been a proven method to increasing staff satisfaction and empowering lifelong learning. The research
Bittles, Natalie
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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