Results 51 to 60 of about 10,670 (255)

Integration of six sigma with lean production: an analysis through multiple cases

Revista Produção Online, 2013
The intense competition between markets has taken companies, regardless of their size, to implement one or more quality improvement programs. One of the main purposes of these programs is the enhancement of company effectiveness and efficiency.
Thiago Henrique Pinheiro, Alisson Christian Scheller, Paulo A Cauchick Miguel   +2 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Circular Economy in Manufacturing: Optimization using Lean Six Sigma [PDF]

E3S Web of Conferences
This research examines the amalgamation of Circular Economy concepts with Lean Six Sigma approaches to enhance manufacturing operations, emphasizing waste minimization, resource efficiency, and economic performance.
Orlov Alexandr K., Hussein Ramy Riad, Subbarayudu Yerragudipadu, Kapoor Tarun, Kumar Pramod, Kansal Lavish, Bhardwaj Nishant, Kumar Yogesh, Lakshmi K. Prasanna   +8 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Lean and/or Six Sigma for process optimization in the perioperative period: an integrative review [PDF]

Revista Brasileira de Enfermagem
Objective: To analyze the evidence on the influence of Lean and/or Six Sigma for process optimization in the perioperative period. Methods: Integrative review carried out in the MEDLINE (PubMed), Web of Science, EMBASE, CINAHL, Scopus and LILACS ...
Lucas Gardim, Fernanda Rodrigues dos Santos, Bruna Moreno Dias, Lívia Barrionuevo El Hetti Fuentes, Renata Cristina de Campos Pereira Silveira, Andrea Bernardes   +5 more
doaj   +1 more source

The use of Lean Six-Sigma tools in the improvement of a manufacturing company – case study

Production Engineering Archives, 2020
Handicraft production is usually chaotic and difficult to monitor, since its products and manufacturing processes are complex. As all the manufacturing steps rely on varied skill levels of the workers, the situation is even more stochastic.
Tran Tuan-Anh, Luu-Nhan Khai, Ghabour Rajab, Daroczi Miklos   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

TOC, Lean, Six Sigma Are Complementary? [PDF]

Ovidius University Annals: Economic Sciences Series, 2018
Improving the performance of a company, whether it be services or production, depends on a detailed understanding of its structure to survive to world-wide competition.
Bostan Rebeca Ioana
doaj